Evidence map›Paper›PMID 42438595›Full record

ReviewInternational journal of nanomedicine2026

Nanobiosensors for Rheumatoid Arthritis Biomarkers: Advances and Clinical Translational Potential.

Xiaoyong Zhang, Xuewu Song, Mingyue Chen, Yifei Lei, Jinqi Li

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyong ZhangDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Xuewu SongDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Mingyue ChenDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Yifei LeiDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Jinqi LiDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article summarizes the development of nanobiological sensors in detecting markers such as serological antibodies related to rheumatoid arthritis(RA) and compares the performance of sensing platforms. In the laboratory, sensing platforms constructed with materials like gold nanoparticles have achieved detection sensitivities from femtomolar to picomolar levels, and some studies have initially verified their availability in samples. In the field of clinical transformation, electrochemical nanobiological sensors are expected to achieve point-of-care testing for RA soon, and optical detection can be used as a high-end platform in central laboratories in the medium term. However, most sensors are at the preclinical verification stage and face many significant challenges. Clinical transformation needs to address overall issues, such as sample pretreatment. This article also explores possible future trends to help provide technical and theoretical support for early diagnosis and treatment of RA.

Indexed as

Arthritis, RheumatoidBiosensing TechniquesNanotechnologyAnimalsBiomarkersGoldHumansMetal NanoparticlesTranslational Research, BiomedicalBiomarkersGoldantibody detectionbiomarkersearly diagnosisnanobiosensorsrheumatoid arthritis

Identifiers

PMID42438595
PMCPMC13356857

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.