Evidence map›Paper›PMID 42438794›Full record

ArticleNorth American Spine Society journal2026

Impact of solid organ transplant on postoperative outcomes following lumbar spine fusion surgery: A propensity-matched retrospective cohort analysis.

Vu Bui, Kevin Yoon, Theodore Quan, Christopher P Bellaire, Jonathan P Japa, Mark Ehioghae, Addisu Mesfin

Abstract read
In one paragraph

Article in North American Spine Society journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vu BuiDepartment of Orthopaedics, Albany Medical College, 43 New Scotland Ave, Albany, NY 12208, United States.
Kevin YoonDepartment of Orthopaedics, MedStar Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, United States.
Theodore QuanDepartment of Orthopaedics, George Washington University, 2300 M ST NW, Washington, DC 20037, United States.
Christopher P BellaireDepartment of Orthopaedics, MedStar Georgetown University Hospital, 3800 Reservoir Rd NW, Washington, DC 20001, United States.
Jonathan P JapaDepartment of Orthopaedics, MedStar Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, United States.
Mark EhioghaeDepartment of Orthopaedics, MedStar Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, United States.
Addisu MesfinDepartment of Orthopaedics, MedStar Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: SOT recipients represent a complex and vulnerable population. The physiologic effects of chronic immunosuppression may predispose these patients to adverse postoperative events, yet large-scale analyses of lumbar spine fusion outcomes in this group remain limited. Methods: Adults over 18 years of age who underwent lumbar spine fusion between 2015 and 2024 were identified through procedural coding in the TriNetX database. Patients with a history of SOT were matched 1:1 to non-transplant controls based on baseline demographics and comorbidities. Postoperative complications were evaluated using statistical tools integrated within the database. Results: After 1:1 propensity score matching, each cohort included 408 patients. At 90 days, SOT patients had higher odds of wound dehiscence (OR 2.33, 95% CI 1.17-4.67), emergency department utilization (OR 1.86, 95% CI 1.26-2.74), and overall medical complications (OR 1.98, 95% CI 1.18-3.30) compared to matched non-SOT controls. At 1 year, transplant recipients had increased rates of reoperation (OR 2.2, CI 1.055-4.59) and pseudoarthrosis (OR 1.76, CI 1.38-2.58). Conclusions: Increased morbidity associated with SOT was reflected by the higher risk for medical complications and wound complications in the short term. Long-term physiologic changes secondary to long-term immunosuppressive therapy were also represented by long-term surgical complications. Our findings highlight a need for a tailored, interdisciplinary approach for surgical planning and postoperative care for this high-risk patient population.

Indexed as

ImmunocompromisedLumbar fusionLumbar spinePseudoarthrosisSolid organ transplantSpine surgery

Identifiers

PMID42438794
PMCPMC13356781

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.