Evidence mapPaperPMID 42439039Full record

ReviewBiomaterials science2026

Nature-inspired biomaterial innovations to counter medical device-associated infections.

Zehui Han, Dacheng Ren

Abstract readReview
In one paragraph

Review in Biomaterials science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zehui HanDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA.
Dacheng RenDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA.ORCID http://orcid.org/0000-0002-6517-906X

Funding

Controlling Catheter-Associated Urinary Tract Infections Using Smart Catheters with Rationally Designed Active TopographiesR01EB030621 · NIBIB · SYRACUSE UNIVERSITY · PI REN, DACHENG · 2021 to 2024
$1.5M
Optogenetic Control of Bacterial Persistence to Study Biomaterial InfectionsR21AI185651 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI REN, DACHENG · 2024 to 2025
$441k
NIAID NIH HHS R21 AI185651NIBIB NIH HHS R01 EB030621
6 · The paper itself

Abstract

Medical device-associated infections remain challenging in modern medicine because abiotic material surfaces are prone to bacterial colonization and biofilm formation, leading to high-level tolerance to antibiotics. The ineffectiveness of antibiotic therapy and the rapid rise of antimicrobial resistance have driven efforts to develop advanced material designs for medical devices. To meet biocompatibility and long-term performance needs, bio-inspired design has emerged as a promising strategy. From material composition and surface coating to surface texture, numerous designs have been engineered to reduce bacterial adhesion and biofilm formation. To overcome the limitation of static surface modification against established biofilms, dynamic surface designs have also been pursued in recent years. Here, we review current bio-inspired surface designs for biofilm control and highlight emerging dynamic, multifunctional strategies for the next generation of infection-resistant medical devices.

Indexed as

Biocompatible MaterialsEquipment and SuppliesProsthesis-Related InfectionsAnimalsAnti-Bacterial AgentsBacterial AdhesionBiofilmsHumansSurface PropertiesAnti-Bacterial AgentsBiocompatible Materials

Identifiers

PMID42439039
PMCPMC13358812

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.