Evidence map›Paper›PMID 42439912›Full record

ArticlePediatric cardiology2026

Outcome of Patients with Single Ventricles who Initially did not Indicate Fontan Completion After Stage II Palliation.

Carolin Niedermaier, Cornelius Przybilla, Thibault Schaeffer, Muneaki Matsubara, Christina Ruda, Jonas Palm, Nicole Piber, Peter Ewert, Jürgen Hörer, Masamichi Ono

Abstract read
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In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carolin Niedermaier *Department of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Cornelius Przybilla *Department of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Thibault SchaefferDepartment of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Muneaki MatsubaraDepartment of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Christina RudaDepartment of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Jonas PalmDepartment of Pediatric Cardiology and Congenital Heart Disease, TUM University Hospital, German Heart Center, Munich, Germany.
Nicole PiberDepartment of Cardiovascular Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Peter EwertDepartment of Pediatric Cardiology and Congenital Heart Disease, TUM University Hospital, German Heart Center, Munich, Germany.
Jürgen HörerDepartment of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany.
Masamichi OnoDepartment of Congenital and Pediatric Heart Surgery, TUM University Hospital, German Heart Center, Munich, Germany. ono@dhm.mhn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite an early-staged Fontan completion strategy, certain patients after bidirectional cavopulmonary shunt (BCPS) could not undergo swift Fontan completion. This study aimed to clarify the clinical course of these patients. Among all infants with univentricular hearts who underwent BCPS between 1998 and 2022, those who could not undergo the Fontan completion at the initial assessment were identified. The reasons, clinical course, and delayed Fontan completion of these patients were evaluated. A total of 491 patients underwent cardiac catheterization for evaluation of Fontan completion at a median age of 1.8 (1.6-2.3) years and 1.4 (1.2-1.9) years after BCPS. Among them, 470 patients underwent subsequent Fontan (Group F), and 21 patients did not (Group C). There were various reasons, including left pulmonary artery stenosis in 14 patients, high pulmonary artery pressure (PAP) in 7, significant atrioventricular valve regurgitation in 6, and systemic ventricular dysfunction in 5. Delayed Fontan completion was performed in 16 patients at a median age of 5.5 (3.7-5.9) years. Survival at 5 years was 90.9% in Group C and 97.2% in Group F (p = .005). A need for additional pulmonary blood flow (APBF) after BCPS (p = .015) and higher PAP at initial assessment (p = .003) were risk factors for delaying Fontan completion. Left pulmonary artery stenosis requiring APBF and high PAP were contraindications to early Fontan completion. Delayed Fontan completion was possible in most patients with acceptable outcomes, suggesting improvement of Fontan candidacy during follow-up.

Indexed as

Additional pulmonary blood flowBidirectional cavopulmonary shuntDelayed Fontan completionLeft pulmonary artery stenosisPulmonary artery pressure

Identifiers

PMID42439912

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.