Association between long-term exposure to environmental coarse particulate matter and the prevalence of thyroid disorders: a cross-sectional study in China.

Changyuan Liu, Jie Li, Bingxin You, Zhongyan Shan, Weiping Teng, Yongze Li

Abstract read

In one paragraph

Article in Journal of endocrinological investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Changyuan LiuDepartment of Endocrinology and Metabolism, The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China.

Jie LiGlobal Health Research Centre, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.

Bingxin YouSchool of Management, University College London, London, UK.

Zhongyan ShanDepartment of Endocrinology and Metabolism, The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China. cmushanzhongyan@163.com.

Weiping TengDepartment of Endocrinology and Metabolism, The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China. twp@vip.163.com.

Yongze LiDepartment of Endocrinology and Metabolism, The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China. yzli87@cmu.edu.cn.

Funding

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College (Grant No. 15010010589)National Key R&D Program of China (No. 2023YFC2508300 and 2023YFC2508305)National Natural Science Foundation of China (Grant No. 82000753 and 82470826)the Research Fund for Public Welfare from the National Health and Family Planning Commission of China (Grant No. 201402005)

6 · The paper itself

Abstract

backgroundEvidence linking long-term exposure to particulate matter with thyroid dysfunction is increasing, but data on particulate matter 10 micrometers or less (PM10) exposure and thyroid disorders remain limited.

methods73,900 subjects aged ≥ 18 years from a nationwide population-based study were included. Thyroid disorders were determined using standardized biochemical testing and thyroid ultrasound examination. Individual long-term PM10 exposure was estimated at a 1 × 1 km spatial resolution using a Space-Time Extra Trees model, and the five-year average concentration preceding enrollment was assigned to each participant's residential address. Weighted estimates were calculated to account for the complex sampling design.

resultsThe average long-term exposure to PM10 at residential addresses was 111.74 µg/m

conclusionLong-term PM10 exposure was associated with higher odds of overt hypothyroidism, subclinical hypothyroidism, autoimmune thyroiditis, and TgAb positivity among Chinese adults. These findings suggest that coarse particulate pollution may be a modifiable environmental factor related to hypothyroidism and thyroid autoimmunity.

Indexed as

Air pollutionHypothyroidismParticulate matterPM10Thyroglobulin antibodyThyroid autoimmunityThyroid disorders

Identifiers

PMID42440239

DOI10.1186/s41021-026-00357-z

What Socratic holds

Textmetadata

Read underepoch 390

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None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.