Evidence map›Paper›PMID 42441239›Full record

ArticleRSC advances2026

Lipophilic mono-guanidines

Randima D De Silva Weerakonda Arachchige, Sarah R Marshall, Hassan Gneid, Nathalie Busschaert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Randima D De Silva Weerakonda ArachchigeDepartment of Chemistry, Tulane University New Orleans LA 70118 USA nbusschaert@tulane.edu.
Sarah R MarshallDepartment of Chemistry, Tulane University New Orleans LA 70118 USA nbusschaert@tulane.edu.
Hassan GneidDepartment of Chemistry, Tulane University New Orleans LA 70118 USA nbusschaert@tulane.edu.
Nathalie BusschaertDepartment of Chemistry, Tulane University New Orleans LA 70118 USA nbusschaert@tulane.edu.ORCID https://orcid.org/0000-0002-3612-3382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic anion transporters (anionophores) can collapse ion gradients and have been widely explored as candidate therapeutics for channelopathies and cancer, yet their potential as antibacterial agents remains comparatively underdevelopped. Here, we systematically compare lipophilic mono-guanidines with isosteric mono-ureas and mono-thioureas, evaluating anion binding, membrane transport, lipid association and antibacterial activity. Chloride transport experiments in POPC show that CF

Identifiers

PMID42441239
PMCPMC13334524

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.