Evidence mapPaperPMID 42445844Full record

ReviewDevelopment & reproduction2026

Inflammation Disrupts Ganglioside Expression during Early Embryonic Development in Institute of Cancer Research (ICR) Mice: Protective Effects of Melatonin.

Hyo Gyeong Yun, Eun Bin Song, Dong Hoon Kwak, Ki Kwan Kim, Min Young Kim, Young-Kug Choo

Abstract readReview
In one paragraph

Review in Development & reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyo Gyeong YunDepartment of Biological Science, College of Health Sciences, Wonkwang University, Iksan 54538, Korea.ORCID https://orcid.org/0009-0007-9319-7031
Eun Bin SongDepartment of Biological Science, College of Health Sciences, Wonkwang University, Iksan 54538, Korea.ORCID https://orcid.org/0009-0007-1930-4572
Dong Hoon KwakRed-Green Bioconvergence Institute, ORGANOIDSCIENCES Ltd., Iksan 54538, Korea.ORCID https://orcid.org/0000-0001-9820-3137
Ki Kwan KimDepartment of Biological Science, College of Health Sciences, Wonkwang University, Iksan 54538, Korea.ORCID https://orcid.org/0009-0008-0236-7929
Min Young KimDepartment of Biological Science, College of Health Sciences, Wonkwang University, Iksan 54538, Korea.ORCID https://orcid.org/0009-0005-9809-6753
Young-Kug ChooDepartment of Biological Science, College of Health Sciences, Wonkwang University, Iksan 54538, Korea.ORCID https://orcid.org/0000-0003-3065-485X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation adversely affects reproductive function and early embryonic development; however, whether inflammatory conditions are associated with alterations in ganglioside expression during early embryogenesis remains unclear. The present study aimed to investigate whether lipopolysaccharide (LPS)-induced chronic inflammation is associated with alterations in ovarian function and early embryonic developmental competence in Institute of Cancer Research (ICR) mice, and whether subsequent melatonin intervention is accompanied by a partial recovery trend. Embryonic developmental competence was evaluated by superovulation and

Indexed as

Blastocyst embryosGangliosidesInflammationIn vitro fertilization (IVF)Ovary

Identifiers

PMID42445844
PMCPMC13357662

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.