ArticleJACC. Case reports2026
Dynamic Resolution of Coronary Vasospasm: The Clasp-Knife Sign.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundCoronary vasospasm may mimic acute coronary occlusion and ST-segment elevation myocardial infarction, potentially leading to unnecessary interventions if not recognized. CASE SUMMARY: A 32-year-old woman with no prior medical history presented with acute chest pain and inferior ST-segment elevation. Emergency coronary angiography demonstrated apparent complete occlusion of the proximal right coronary artery with absent distal flow. Before any mechanical intervention, intracoronary nitroglycerin was administered, resulting in abrupt restoration of vessel patency with normalization of luminal caliber and TIMI flow grade 3. This dynamic change created a characteristic appearance resembling the sudden opening of a clasp knife. The patient was managed conservatively with vasodilator therapy and remained clinically stable. DISCUSSION: This case highlights a distinctive angiographic manifestation of coronary vasospasm. Recognition of this phenomenon, termed the clasp-knife sign, may help differentiate vasospastic occlusion from thrombotic coronary obstruction and prevent unnecessary coronary intervention.
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