Evidence map›Paper›PMID 42449029›Full record

ArticleClinical oral investigations2026

Correlation between MRI disc morphology and temporomandibular joint osteoarthritis in patients with temporomandibular joint disc displacement with reduction: a cross-sectional CBCT-MRI combined study.

Xingyu Lyu, Ruiye Bi, Yuke Shi, Jiannan Zhao, Jia Kang, Xiaoqing Li, Xianglong Han, Mingjun Ren, Yiru Wang, Abotaleb Bassam and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xingyu LyuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Ruiye BiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Yuke ShiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Jiannan ZhaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Jia KangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Xiaoqing LiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Temporomandibular Joint, Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Xianglong HanState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Mingjun RenState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Yiru WangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Temporomandibular Joint, Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Abotaleb BassamDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ibb University, Ibb, Yemen.
Songsong ZhuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. ZSS_1977@163.com.
Pinyin CaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. woshicin@126.com.ORCID https://orcid.org/0000-0001-5237-4870

Funding

National Key Research and Development Program of China No. 2023YFC2509200National Natural Science Foundation of China No. 82301109
6 · The paper itself

Abstract

objectiveThis study aims to classify the morphology and position of the temporomandibular joint disc in patients with disc displacement with reduction (ADDWR) on MRI and explore their correlation with temporomandibular joint osteoarthritis(TMJOA), in order to identify ADDWR patients with a higher prevalence of TMJOA. METHODS AND MATERIALS: This cross-sectional study consecutively enrolled 1577 patients with ADDWR at West China Stomatological Hospital, Sichuan University, from December 2022 to March 2026, with all imaging data prospectively collected according to a predefined protocol. The morphology and position of the TMJ disc were classified using oblique sagittal MRI images in both the opened and closed mouth positions. Among these, 502 patients with complete MRI and CBCT data were included in the cross-sectional association analysis of TMJOA using binary logistic regression.

resultsBased on oblique sagittal MRI images taken with the mouth closed, disc morphology was classified into five types: biconcave, angulated, elongated, short and thick, and anterior thickened; disc position was classified as complete anterior displacement or partial anterior displacement according to the location of the posterior margin of the disc's posterior band relative to the tip of the condyle. MRI images taken with the mouth open classified disc morphology into biconcave and elongated types, and disc position into normal position, overhead, and anterior displaced. Among 502 patients (631 joints), the prevalence of TMJOA was 8.08% (51/631). Binary logistic regression analysis revealed that four closed mouth MRI features were independently associated with TMJOA. Compared with the biconcave reference group, the elongated disc (OR = 8.04, 95% CI: 3.03-21.32, P < 0.001), the short and thick disc (OR = 49.27, 95% CI: 11.56-210.03, P < 0.001), a preliminary finding based on a limited sample of 15 joints, and the anterior thickened disc (OR = 10.25, 95% CI: 2.52-41.64, P = 0.001) were each associated with a significantly increased prevalence of TMJOA. Complete anterior disc displacement in the closed mouth position (OR = 6.24, 95% CI: 2.74-14.24, P < 0.001) was also identified as an imaging feature associated with higher prevalence of TMJOA. In contrast, no opened mouth MRI features including disc morphology, disc position, or medial/lateral displacement-showed a significant association with TMJOA (all P > 0.05).

conclusionsThe morphology of the TMJ disc at the closed position (elongated, short and thick and anterior thickened disc) and complete anterior displacement are associated factors of TMJOA in patients with ADDWR. CLINICAL RELEVANCE: Patients with ADDWR who exhibit the aforementioned closed mouth MRI features may benefit from increased clinical awareness and further evaluation to address the potential risk of TMJOA‑related bone changes.

Indexed as

Cone-Beam Computed TomographyJoint DislocationsMagnetic Resonance ImagingOsteoarthritisTemporomandibular Joint DiscTemporomandibular Joint DisordersAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedAnterior disc displacement with reductionDisc morphologyMRITemporomandibular disordersTemporomandibular joint osteoarthritis

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.