Evidence map›Paper›PMID 42449057›Full record

ArticleMolecular neurobiology2026

Ficus deltoidea Preserves Hippocampal Neuronal Integrity and Redox Balance in Oxidative Stress-Driven Alzheimer's Disease-Like Rat Model.

Alhaji Modu Bukar, Che Mohd Nasril Che Mohd Nassir, Michael Ayuba, Sushmita Devi Manoharan, Abdulhamid Sani Usman, Babagana Isa Umar, Zaw Myo Hein, Mohamad Aris Mohd Moklas, Muhammad Zulfadli Mehat, Hafizah Abdul Hamid

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alhaji Modu BukarDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Che Mohd Nasril Che Mohd NassirDepartment of Anatomy and Physiology, School of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin, 20400, Kuala Terengganu, Terengganu, Malaysia. nasrilnassir@unisza.edu.my.
Michael AyubaDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Sushmita Devi ManoharanDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Abdulhamid Sani UsmanDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Babagana Isa UmarDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Zaw Myo HeinDepartment of Basic Medical Sciences, College of Medicine, Ajman University, P.O. Box 346, Ajman, United Arab Emirates.
Mohamad Aris Mohd MoklasDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Muhammad Zulfadli MehatDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Hafizah Abdul HamidDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia. a_hafizah@upm.edu.my.ORCID https://orcid.org/0000-0001-5333-4694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide, with oxidative stress playing a central role in its pathogenesis. Ficus deltoidea (FD), a medicinal plant rich in flavonoids vitexin and isovitexin, possesses potent antioxidant and anti-inflammatory properties, yet its neuroprotective efficacy in AD remains incompletely characterized. This study investigated the protective effects of FD in a D-galactose- and aluminum chloride (AlCl

Indexed as

Alzheimer DiseaseFicusHippocampusNeuronsOxidative StressPlant ExtractsAluminum ChlorideAnimalsAntioxidantsDisease Models, AnimalGalactoseMaleMaze LearningNeuroprotective AgentsOxidation-ReductionRatsAluminum ChlorideAntioxidantsGalactoseNeuroprotective AgentsPlant ExtractsAlzheimer’s diseaseCognitive dysfunctionFicus deltoideaHippocampusNeuroprotectionOxidative stressTherapy

Identifiers

PMID42449057
PMCPMC13369726

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.