Evidence mapPaperPMID 42449934Full record

ArticleInternational journal of molecular sciences2026

miR-23a-3p as a Biomarker Associated with Prediabetes in People Living with HIV: An Integrative Analysis of Inflammatory, Metabolic, and Insulin Resistance Signatures.

Paula Catalina Méndez-Ríos, Yusnier Lázaro Díaz-Rodríguez, Luis F Jave-Suarez, Luz A González-Hernández, Jaime F Andrade-Villanueva, Monserrat Álvarez-Zavala, Pedro Martínez-Ayala, Vida V Ruiz-Herrera, Elsa Janneth Anaya-Ambriz, Karina Sánchez-Reyes

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paula Catalina Méndez-RíosUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Programa de Doctorado en Ciencias en Biología Molecular en Medicina, Guadalajara 44340, Mexico.ORCID 0009-0000-9280-3617
Yusnier Lázaro Díaz-RodríguezUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Programa de Maestría en Microbiología Médica, Guadalajara 44340, Mexico.ORCID 0000-0002-7730-0525
Luis F Jave-SuarezInstituto Mexicano del Seguro Social, Centro de Investigación Biomédica de Occidente, (CIBO-IMSS), División de Inmunología, Guadalajara 44340, Mexico.ORCID 0000-0001-6209-5031
Luz A González-HernándezUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Departamento de Clínicas Médicas, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Guadalajara 44350, Mexico.ORCID 0000-0002-7163-0566
Jaime F Andrade-VillanuevaUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Departamento de Clínicas Médicas, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Guadalajara 44350, Mexico.ORCID 0000-0003-1948-655X
Monserrat Álvarez-ZavalaUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Departamento de Clínicas Médicas, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Guadalajara 44350, Mexico.ORCID 0000-0003-0242-239X
Pedro Martínez-AyalaHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara 44350, Mexico.ORCID 0000-0002-0505-6340
Vida V Ruiz-HerreraHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara 44350, Mexico.
Elsa Janneth Anaya-AmbrizUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Programa de Doctorado en Microbiología Médica, Guadalajara 44340, Mexico.ORCID 0000-0001-9384-201X
Karina Sánchez-ReyesUniversidad de Guadalajara, Centro Universitario de Ciencias de La Salud, Departamento de Clínicas Médicas, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Guadalajara 44350, Mexico.ORCID 0000-0001-6839-0293

Funding

Secretaría de Ciencia, Humanidades, Tecnología e Innovación CF-2023-I-1079University of Guadalajara PIN 2021-II
6 · The paper itself

Abstract

People living with HIV (PLWHIV) have an increased risk of developing metabolic disorders, including type 2 diabetes (T2D), partly driven by chronic low-grade inflammation and immune dysregulation. This study evaluated the potential role of circulating miR-23a-3p as a possible early biomarker of prediabetes (preT2D) in PLWHIV. In this cross-sectional study, 80 adults were divided into five groups (

Indexed as

HIV InfectionsInflammationInsulin ResistanceMicroRNAsPrediabetic StateAdultBiomarkersCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedBiomarkersMicroRNAsMIRN23a microRNA, humanbiomarkerschronic inflammationinsulin resistance (IR)miR-23a-3ppeople living with HIV (PLWHIV)prediabetes (preT2D)type 2 diabetes (T2D)

Identifiers

PMID42449934
PMCPMC13361635

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.