Evidence map›Paper›PMID 42450005›Full record

ArticleInternational journal of molecular sciences2026

High-Glucose-Induced Metabolic and Epithelial Stress in Grass Carp Intestinal Epithelial Cells Associated with Methylation-Related Transcriptional Responses.

Linjie Qian, Wenqiang Jiang, Yan Lin, Siyue Lu, Xianping Ge, Linghong Miao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linjie QianWuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China.
Wenqiang JiangKey Laboratory for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China.
Yan LinKey Laboratory for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China.
Siyue LuKey Laboratory for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China.
Xianping GeWuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China.
Linghong MiaoWuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China.ORCID 0000-0001-8008-3560

Funding

China Agriculture Research System CARS-45National Key Research and Development Plan Program of China 2022YFD2400600/2022YFD2400603Science and Technology Innovation Team Grant No. 2023TD63
6 · The paper itself

Abstract

High-glucose exposure impairs intestinal metabolic homeostasis and barrier integrity in fish, but the transcriptional responses associated with high-glucose adaptation in fish intestinal epithelial cells remain incompletely understood. This study investigated whether exogenous 5-methylcytosine (5MC) alleviates high-glucose-induced metabolic and epithelial stress in grass carp (

Indexed as

CarpsDNA MethylationEpithelial CellsGlucoseIntestinal MucosaStress, PhysiologicalTranscription, Genetic5-MethylcytosineAnimalsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BGene Expression RegulationMolecular Docking SimulationNF-kappa BSodium-Glucose Transporter 15-MethylcytosineDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BGlucoseNF-kappa BSodium-Glucose Transporter 15-methylcytosinednmt3b-cdx1b-sglt1high-glucose stressintestinal epithelial cellstranscriptional response

Identifiers

PMID42450005
PMCPMC13362540

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.