Evidence map›Paper›PMID 42450064›Full record

ArticleInternational journal of molecular sciences2026

Genomic Variability of the HCT116 Cell Line Identified Using Oxford Nanopore Sequencing.

Regina Mikheeva, Pavel Leonov, Maksim Koryukov, Ekaterina Ruleva, Ekaterina Karabut, Andrey Kechin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Regina MikheevaInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.ORCID 0009-0006-6496-7466
Pavel LeonovInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.ORCID 0009-0009-6735-1263
Maksim KoryukovInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.ORCID 0000-0003-0223-7303
Ekaterina RulevaInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Ekaterina KarabutInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Andrey KechinInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.

Funding

Russian Science Foundation 25-74-10103
6 · The paper itself

Abstract

HCT116 is a colorectal cancer cell line frequently used in anti-tumor drug development experiments as well as in studies of the molecular machinery of eukaryotic cells. It is well characterized by the presence of several single-nucleotide and short mutations in multiple oncogenes and tumor suppressor genes, including

Indexed as

Colorectal NeoplasmsDNA Copy Number VariationsGenome, HumanNanopore SequencingGene RearrangementGenomicsHCT116 CellsHumanscell linecolorectal cancergenomic rearrangementsHCT116single-nucleotide variantsstructural variants

Identifiers

PMID42450064
PMCPMC13360728

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.