Evidence map›Paper›PMID 42450088›Full record

ArticleInternational journal of molecular sciences2026

Serum Pharmacochemistry-Guided DARTS-MS Profiling Reveals Potential Mechanisms of

Jiacheng Hu, Yujie Qiao, Gaoxiang Lei, Xiangyun Gai, Qingqing Xia, Qiuqin Hu, Haotian Sun, Hongmai Wang, Zhanqiang Li, Yuefu Zhao and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiacheng HuDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.ORCID 0009-0003-0371-0630
Yujie QiaoDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Gaoxiang LeiDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Xiangyun GaiDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Qingqing XiaDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Qiuqin HuDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Haotian SunDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Hongmai WangDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Zhanqiang LiPlateau Medicine Research Center, Qinghai University, Xining 810001, China.ORCID 0000-0002-6482-3255
Yuefu ZhaoDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.
Jinyu WangDepartment of Pharmacy, Qinghai Minzu University, Xining 810007, China.

Funding

Science and Technology Department of Qinghai Province 2025Science and Technology Department of Qinghai Province 2025-ZJ-723
6 · The paper itself

Abstract

Hypoxic pulmonary hypertension (HPH) is a progressive vascular disease characterized by an abnormal increase in pulmonary arterial pressure resulting from pulmonary vasoconstriction and pulmonary vascular remodeling (PVR). Excessive proliferation and migration of pulmonary artery smooth muscle cells (PASMCs) are key drivers of PVR.

Indexed as

CaraganaHypertension, PulmonaryHypoxiaPlant ExtractsAnimalsCell MovementCell ProliferationMaleMass SpectrometryMuscle, Smooth, VascularMyocytes, Smooth MuscleProteomicsPulmonary ArteryRatsRats, Sprague-DawleyVascular RemodelingPlant ExtractsCaragana jubata (Pall.) Poir.chemoproteomicsDARTS-MShypoxic pulmonary hypertensionpulmonary artery smooth muscle cellsserum pharmacochemistryvascular remodeling

Identifiers

PMID42450088
PMCPMC13361411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.