Evidence map›Paper›PMID 42450345›Full record

ArticleInternational journal of molecular sciences2026

Acclimatization Effects of

Karen Flores, Karem Arriaza, Eduardo Pena, Isaac Cortes, Maite Villalobos, Samia El Alam

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karen FloresHigh Altitude Medicine Research Center (CEIMA), Arturo Prat University, Iquique 1110939, Chile.
Karem ArriazaHigh Altitude Medicine Research Center (CEIMA), Arturo Prat University, Iquique 1110939, Chile.
Eduardo PenaHigh Altitude Medicine Research Center (CEIMA), Arturo Prat University, Iquique 1110939, Chile.ORCID 0000-0003-2664-1722
Isaac CortesMathematic Department, Engineer Faculty, Atacama University, Copiapó 1530000, Chile.
Maite VillalobosCenter for Applied Research and Innovation in Biological Sciences, Faculty of Renewable Natural Resources, Arturo Prat University, Huayquique Campus, Iquique 1100000, Chile.
Samia El AlamHigh Altitude Medicine Research Center (CEIMA), Arturo Prat University, Iquique 1110939, Chile.ORCID 0000-0002-7501-5077

Funding

FIC GORE-TARAPACA grant BIP-40047365-0
6 · The paper itself

Abstract

Exposure to high altitudes for hours or days is defined as acute hypobaric hypoxia (AHH) condition, which rapidly engages adjustments such as signaling pathways involving inflammation, immune modulation and oxidative stress, whose dysregulation has been described as contributing to the pathophysiology of high-altitude illnesses, due to insufficient acclimatization, such as developing acute mountain sickness (AMS). Given its traditional high-altitude use and bioactive properties,

Indexed as

AcclimatizationAltitude SicknessHypoxiaPlant ExtractsSenecioAnimalsCytokinesFemaleInterleukin-1betaInterleukin-6LungNF-kappa BOxidative StressRatsRats, WistarVascular Endothelial Growth Factor ACytokinesInterleukin-1betaInterleukin-6NF-kappa BPlant ExtractsVascular Endothelial Growth Factor Aacclimatizationacute hypobaric hypoxiainflammationlung injurySenecio nutans

Identifiers

PMID42450345
PMCPMC13361913

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.