Evidence map›Paper›PMID 42450403›Full record

ArticleFoods (Basel, Switzerland)2026

Effects of Medium-Chain Versus Medium- and Long-Chain Triglycerides, Combined with Carotenoids, in a High-Fat Diet on Obese Mice.

Ruihong Ge, Keyu Tu, Jinyang Li, Liang Wu, Yongjian Ge, Yongkang Niu, Shiyu Chen, Qinglong Wu, Ruozhen Wang, Shiqing Chen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ruihong GeSchool of Public Health, Shanghai Jiao Tong University, Shanghai 200025, China.ORCID 0000-0001-5026-4563
Keyu TuCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Jinyang LiCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Liang WuCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Yongjian GeCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Yongkang NiuCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Shiyu ChenCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Qinglong WuCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Ruozhen WangCollege of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai 200025, China.
Shiqing ChenPalm Oil Research and Technical Service Institute, Malaysian Palm Oil Board, Shanghai 201108, China.
Yoong JunhaoPalm Oil Research and Technical Service Institute, Malaysian Palm Oil Board, Shanghai 201108, China.
Hui WangSchool of Public Health, Shanghai Jiao Tong University, Shanghai 200025, China.

Funding

Malaysian Palm Oil Board PORTSIM 095/2022Shanghai Jiao Tong University 2023HX012
6 · The paper itself

Abstract

While medium-chain triglycerides (MCTs), medium- and long-chain triglycerides (MLCTs), and carotenoids individually possess anti-obesity properties, the synergistic metabolic regulatory effects of their combined intervention remain under-investigated. This study explored the effects of MCTs or structured MLCTs combined with natural carotenoids on high-fat diet (HFD)-induced obese mice. After establishing obesity in C57BL/6J mice using a 60% HFD, a ten-week intervention was conducted using 45% HFD containing 150 mg/kg carotenoids across three groups: MCT-C, MLCT-C, and a physical mixture of MCTs and long-chain triglycerides plus carotenoids (MCT+LCT-C), alongside a low-fat diet (LFD) control. Results showed that among the three HFD-fed intervention groups, the MCT-C group had the lowest body weight with significantly lower fat mass, fat pad coefficient, and adipocyte area, but higher liver coefficient and serum alanine aminotransferase levels compared to the LFD control group (

Indexed as

carotenoidsgut microbiotalipid metabolismmedium- and long-chain triglyceridesobesity

Identifiers

PMID42450403
PMCPMC13361576

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.