ReviewBiology2026
Ionic Gelation for Nano-Delivery of Sulforaphane in Animal Feed: A Conceptual Review of Stability, Efficacy, and Translation Potential.
Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulforaphane (SFN), a bioactive compound sourced from cruciferous vegetables, offers significant antioxidant and anti-inflammatory benefits yet its stability in animal feed is a challenge. Nanotechnology-based encapsulation, specifically ionic gelation, has demonstrated efficacy in improving the stability and bioavailability of SFN. This review examines the application of natural polymers such as chitosan and alginate in ionic gelation for the encapsulation of SFN. It also discusses how these polymers can prevent SFN from degrading while traversing the digestive tract. Encapsulation strategies for SFN have been associated with improved bioavailability, with absorption reported in experimental modules, to modulate immune-related and oxidative-stress pathways. However, challenges persist in identifying optimal methods for encapsulating various species, including enhancing encapsulation effectiveness, particle size, and controlled release mechanisms. Additionally, regulatory concerns regarding the safety and environmental impacts of nanoparticles in feed must be addressed. Future research should focus on improving encapsulation techniques and ensuring the safe application of SFN-loaded nanocarriers in livestock feed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.