Transcriptional Mapping of the Human Cannabinoid Receptor 1 (

Alonso Cortez-Resendiz, Shivani S Godbole, Nurgul Carkaci-Salli, Kent E Vrana, Wesley M Raup-Konsavage

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alonso Cortez-ResendizDepartment of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, Penn State University, Hershey, PA 17033, USA.

Shivani S GodboleDepartment of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, Penn State University, Hershey, PA 17033, USA.

Nurgul Carkaci-SalliDepartment of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, Penn State University, Hershey, PA 17033, USA.

Kent E VranaCenter for Cannabis and Natural Product Pharmaceutics (CCNPP), Penn State College of Medicine, Penn State University, Hershey, PA 17033, USA.ORCID 0000-0003-4902-7733

Wesley M Raup-KonsavageDepartment of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, Penn State University, Hershey, PA 17033, USA.ORCID 0000-0001-9413-9852

Funding

AI-based Mapping of Complex Cannabis Extracts in Pain PathwaysR01AT012053 · NCCIH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Nikolay Dokholyan, KENT E VRANA · 2023 to 2026

$2.4M

Foundation for the National Institutes of Health R01AT012053-01NCCIH NIH HHS R01 AT012053

6 · The paper itself

Abstract

The transcriptional regulation of the cannabinoid receptor 1 (CB1R) by promoter/enhancer elements and transcription factors is an area of cannabinoid research that has historically been understudied. To map the promoter region of the human

Indexed as

Promoter Regions, GeneticReceptor, Cannabinoid, CB1Transcription, GeneticBase SequenceCell LineCyclic AMPGene Expression RegulationGenes, ReporterHEK293 CellsHumansCNR1 protein, humanCyclic AMPReceptor, Cannabinoid, CB1cAMPcannabinoid receptor 1CNR1promotertranscriptional regulation

Identifiers

PMID42451754

DOI10.3390/molecules31132387

PMCPMC13363282

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.