Evidence mapPaperPMID 42452525Full record

ReviewJournal of clinical medicine2026

Nutritional Status and Cardiovascular Disease in Older Adults: Clinical Perspectives from Mechanisms to Management.

Iris Parrini, Carmelo Massimiliano Rao, Fabiana Lucà, Michele Massimo Gulizia, Roberto Ceravolo, Sandro Gelsomino, Nadia Ingianni, Caterina Patrizia Ceruso, Clementina Silvia Iannì, Maria Teresa Ferrò and 5 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Iris ParriniCardiology Unit, Koelliker Hospital, 10134 Torino, Italy.ORCID 0000-0002-0038-9445
Carmelo Massimiliano RaoCardiology Unit, Santa Maria Degli Ungheresi Hospital, Polistena, 89024 Reggio Calabria, Italy.
Fabiana LucàCardiology Department, Grande Ospedale Metropolitano of Reggio Calabria, 89124 Reggio Calabria, Italy.ORCID 0000-0002-5369-5382
Michele Massimo GuliziaCardiology Department, Garibaldi Nesima Hospital, 95122 Catania, Italy.
Roberto CeravoloCardiology Unit, Giovanni Paolo II Hospital, 88046 Lamezia Terme, Italy.
Sandro GelsominoCardiothoracic Department, Maastricht University Hospital, 6229 Maastricht, The Netherlands.ORCID 0000-0002-7746-989X
Nadia IngianniCardiologic District, Azienda Sanitaria Provinciale Di Trapani, 91016 Trapani, Italy.
Caterina Patrizia CerusoCardiology Department, Grande Ospedale Metropolitano of Reggio Calabria, 89124 Reggio Calabria, Italy.
Clementina Silvia IannìCardiology Unit, N. Giannettasio Hospital, 87064 Rossano, Italy.
Maria Teresa FerròCardiology Unit, Cetraro-Paola Hospital, 87027 Paola, Italy.
Claudio BilatoCardiology Unit, Arzignano Hospital, 36071 Arzignano, Italy.ORCID 0000-0003-3474-0579
Giovanna GeraciCardiology Department, Sant'Antonio Abate Hospital, Erice, 91016 Trapani, Italy.ORCID 0000-0003-0092-8717
Fabrizio OlivaCardiology Unit, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0009-0004-9459-2488
Federico NardiCardiology Department, Santo Spirito Hospital, Casale Monferrato, 15033 Alessandria, Italy.ORCID 0000-0002-7743-2587
Massimo GrimaldiCardiology Department, General Regional Hospital "F. Miulli", Acquaviva Delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-9347-8884

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional status is a pivotal determinant of health and longevity in ageing populations. Malnutrition, overnutrition, and sarcopenic obesity are increasingly recognised as key modifiers of CV risk in older adults. Beyond caloric imbalance, age-related metabolic, hormonal, and inflammatory changes profoundly influence CV structure and function. Both nutrient deficiency and excess contribute to endothelial dysfunction, oxidative stress, and chronic inflammation, core mechanisms underlying atherosclerosis, heart failure, and frailty. This review analyses the complex interplay between nutrition and cardiovascular diseases in older adults, outlining physiological mechanisms, diagnostic tools for nutritional assessment, and evidence-based dietary strategies aimed at prevention and management. Particular attention is given to the challenges of multimorbidity, polypharmacy, and altered body composition that shape nutritional care in geriatric cardiology.

Indexed as

CV diseasefrailtymalnutritionMediterranean dietnutritionolder adultssarcopenia

Identifiers

PMID42452525
PMCPMC13362827

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.