Evidence mapPaperPMID 42453349Full record

ArticleACS pharmacology & translational science2026

Advanced Spray-Dried Cyanidin Chloride Inhalable Dry Powders with High Aerosol Dispersion Performance and Mitochondrial Bioenergetics Modulation for Targeted Pulmonary Delivery.

Hasham Shafi, Priya Muralidharan, David Encinas-Basurto, Heidi M Mansour

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hasham ShafiCenter for Translational Science, Florida International University, Port St. Lucie, Florida 34987, United States.
Priya MuralidharanSkaggs Pharmaceutical Sciences Center, The University of Arizona R. Ken Coit College of Pharmacy, Tucson, Arizona 85721, United States.
David Encinas-BasurtoSkaggs Pharmaceutical Sciences Center, The University of Arizona R. Ken Coit College of Pharmacy, Tucson, Arizona 85721, United States.
Heidi M MansourCenter for Translational Science, Florida International University, Port St. Lucie, Florida 34987, United States.ORCID https://orcid.org/0000-0003-3993-9210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using an organic solution-based, closed-mode spray drying particle engineering approach, Cyanidin chloride, a natural flavonoid with potent antioxidant and anti-inflammatory properties, was designed into inhalable powders for targeted pulmonary delivery using dry powder inhalers. Two different spraying pump rates of 25% and 50% were used for co-spray drying cyanidin chloride with trehalose dihydrate. In addition to in silico computational predictive modeling, particle-engineered powders were comprehensively characterized for physicochemical properties,

Indexed as

air−liquid interfaceanthocyaninsbiocompatibilityinhaler devicesmitochondrial bioenergeticsparticle engineering design

Identifiers

PMID42453349
PMCPMC13366343

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.