Evidence map›Paper›PMID 42453356›Full record

ArticleBlood red cells & iron2026

Defining and quantifying oxygen delivery potency of blood products.

Stephen C Rogers, Mary Brummet, Kevin V Tobin, Zohreh Safari, Aishwarya Anand, Daniel Bennett, Regina Adao, Elizabeth McAslan, Mette Jacobsen, Anna Parrish and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood red cells & iron, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Stephen C RogersDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0003-1139-4730
Mary BrummetDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.
Kevin V TobinCenter for Translational Medicine, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0003-4364-7333
Zohreh SafariDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0001-5225-713X
Aishwarya AnandDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.
Daniel BennettDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.ORCID 0009-0001-3710-2858
Regina AdaoCenter for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD.
Elizabeth McAslanKaloCyte, Inc, Baltimore, MD.ORCID 0009-0002-4892-0060
Mette JacobsenKaloCyte, Inc, Baltimore, MD.
Anna ParrishKaloCyte, Inc, Baltimore, MD.
Ankita JoshiKaloCyte, Inc, Baltimore, MD.
Esma AlpKaloCyte, Inc, Baltimore, MD.
Elizabeth ZheleznyakovaKaloCyte, Inc, Baltimore, MD.ORCID 0000-0002-1280-6357
Paul W BuehlerDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.
Andre F PalmerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH.
Tanmay SalviWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH.ORCID 0000-0002-2538-3920
Griffin BeyerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH.ORCID 0009-0009-6367-3046
Mohd Asim KhanWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH.ORCID 0000-0002-4698-2332
Antonio RenaldoCenter for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD.ORCID 0009-0001-0238-8008
Ashlee ConwayCenter for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-9000-7366
Tobi RowdenDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.
William McGheeKaloCyte, Inc, Baltimore, MD.
Shelby McCauleyKaloCyte, Inc, Baltimore, MD.
Anirban Sen GuptaDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH.ORCID 0000-0002-5773-0667
Michael A BruckmanHaima Therapeutics LLC, Cleveland, OH.
Christa L PawlowskiHaima Therapeutics LLC, Cleveland, OH.
Susan SheaDepartment of Surgery, Critical Care Medicine, and Bioengineering, University of Pittsburgh, Pittsburgh, PA.
Matthew D NealHaima Therapeutics LLC, Cleveland, OH.ORCID 0000-0001-8931-6236
Philip C SpinellaDepartment of Surgery, Critical Care Medicine, and Bioengineering, University of Pittsburgh, Pittsburgh, PA.
Dipanjan PanDepartments of Biomedical Engineering, Materials Science and Engineering, and Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA.ORCID 0000-0003-0175-4704
Allan DoctorDivision of Pediatric Critical Care, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-6096-6400

Funding

SEPSIS-INDUCED RED CELL DYSFUNCTION (SIRD)R01GM113838 · NIGMS · WASHINGTON UNIVERSITY · PI DOCTOR, ALLAN, MARSHALL, GARLAND ROSS · 2015 to 2019
$4.0M
ErythroMer: Nanoscale BioSynthetic Red Cell SubstituteR44HL135965 · NHLBI · KALOCYTE, INC. · PI ALP, ESMA · 2023 to 2025
$3.0M
Red blood cell ATP export and transfusion in sepsisR01HL161071 · NHLBI · DUKE UNIVERSITY · PI Allan Doctor, TIMOTHY J MCMAHON · 2023 to 2026
$2.7M
ErythroMer: Nanoscale Bio-Synthetic Red Cell SubstituteR42HL135965 · NHLBI · KALOCYTE, INC. · PI MITTAL, NIVESH KUMAR · 2017 to 2019
$2.0M
Preclinical Evaluation of a Peptide-amphiphile Derived Toroidal Oxygen CarrierR01HL173540 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI Narayana Aluru, Paul Werner Buehler · 2025 to 2026
$1.4M
NHLBI NIH HHS R01 HL161071NHLBI NIH HHS R01 HL173540NHLBI NIH HHS R42 HL135965NHLBI NIH HHS R44 HL135965NIGMS NIH HHS R01 GM113838
6 · The paper itself

Abstract

Transfusion is intended to correct anemia when it is believed to either impair adequate oxygen (O

Identifiers

PMID42453356
PMCPMC13367430

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.