Evidence map›Paper›PMID 42453395›Full record

ArticleActa pharmaceutica Sinica. B2026

Chongdeng Shi, Maosen Han, Hui Yang, Xiaotian Zhao, Zuolin Zheng, Huijun Wang, Zhipeng Fu, Kuan Dai, Kun Zhao, Na Li and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chongdeng ShiClinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen 518100, China.
Maosen HanState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Hui YangDepartment of Radiology, Qilu Hospital, Shandong University, Jinan 250012, China.
Xiaotian ZhaoState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zuolin ZhengState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Huijun WangDepartment of Radiology, Qilu Hospital, Shandong University, Jinan 250012, China.
Zhipeng FuState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Kuan DaiNanjing Foreigin Language School Xianlin Campus, Nanjing 210000, China.
Kun ZhaoState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Na LiCollege of Chemistry, Chemical Engineering and Materials Science, Shandong University, Jinan 250012, China.
Yudong SongState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Chen ChenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Fei YangState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Anning LiDepartment of Radiology, Qilu Hospital, Shandong University, Jinan 250012, China.
Xinyi JiangState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, NMPA Center for Innovation and Research in Regulatory Science, Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics, Shandong Basic Science Special Academic Zone(Pharmacy) and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Epstein‒Barr virus (EBV)-induced B-cell overactivation could lead to inflammatory injury to the CNS, which is thought to underlie the initiation and progression of MS. To specifically eradicate these B cells, we report

Indexed as

Autoimmune diseaseB cellCAR-TCNSEAEImmunoengineeringLipid nanoparticlesMultiple sclerosis

Identifiers

PMID42453395
PMCPMC13366321

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.