Evidence map›Paper›PMID 42453605›Full record

ArticleOpen life sciences2026

Time-dependent effects of hypoxia on mitochondrial dynamics, dysfunction and apoptosis in C8-D1A astrocytes.

Youjuan Chen, Jing Hou, Meiyuan Tian, Erwa Hao, Yaogang Zhang, Dengliang Huang, Tao Zhang, Yanyan Ma

Abstract read
In one paragraph

Article in Open life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Youjuan ChenDepartment of Pediatrics, Affiliated Hospital of Qinghai University (Faculty of Clinical Medicine), Xining, 810001, Qinghai Province, China.
Jing HouCentral Laboratory, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai Province, China.
Meiyuan TianCentral Laboratory, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai Province, China.
Erwa HaoDepartment of Pediatrics, Affiliated Hospital of Qinghai University (Faculty of Clinical Medicine), Xining, 810001, Qinghai Province, China.
Yaogang ZhangCentral Laboratory, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai Province, China.
Dengliang HuangCentral Laboratory, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai Province, China.
Tao ZhangDepartment of Rehabilitation Medicine, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai Province, China.
Yanyan MaDepartment of Pediatrics, Affiliated Hospital of Qinghai University (Faculty of Clinical Medicine), Xining, 810001, Qinghai Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the effects of hypoxia on mitochondrial function in C8-D1A astrocytes and to evaluate its association with apoptosis. Mouse C8-D1A astrocytes were allocated to a normoxia group (21 % O

Indexed as

astrocyte apoptosisC8-D1A astrocyteshypoxiamitochondriareactive oxygen species (ROS)

Identifiers

PMID42453605
PMCPMC13367201

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.