Evidence map›Paper›PMID 42453633›Full record

ArticleAPL bioengineering2026

Prediction of arrhythmogenesis in non-ischemic cardiac resynchronization therapy patients.

Alessandra Corda, Massimiliano Maines, Stefano Pagani, Domenico Catanzariti, Maurizio Del Greco, Christian Vergara

Abstract read
In one paragraph

Article in APL bioengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandra CordaLaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, Milano, Italy.ORCID https://orcid.org/0009-0009-6240-0601
Massimiliano MainesCardiology Department, S.M. del Carmine Hospital, APSS Corso Verona, 4, Rovereto 38068, Trento, Italy.ORCID https://orcid.org/0000-0002-2576-1653
Stefano PaganiMOX, Dipartimento di Matematica, Politecnico di Milano, Milano, Italy.ORCID https://orcid.org/0000-0002-6662-3433
Domenico CatanzaritiCardiology Department, S.M. del Carmine Hospital, APSS Corso Verona, 4, Rovereto 38068, Trento, Italy.
Maurizio Del GrecoCardiology Department, S.M. del Carmine Hospital, APSS Corso Verona, 4, Rovereto 38068, Trento, Italy.ORCID https://orcid.org/0000-0002-2728-7844
Christian VergaraLaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, Milano, Italy.ORCID https://orcid.org/0000-0001-9872-5410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to develop a patient-specific computational model to predict the risk of Ventricular Tachycardia (VT) in patients with a Biventricular Cardiac Resynchronization Therapy (BiV-CRT) device. Patients are indeed at risk of developing arrhythmias due to BiV-CRT pacing, a known potential complication that requires preventive evaluation. We consider three non-ischemic fibrotic patients. Patient-specific left ventricle geometries and fibrosis are extracted from Cine-MRI and LGE-MRI. The electrophysiology model, based on the monodomain equation and the Ten Tusscher-Panfilov (TTP06) ionic model, is personalized using pre-operative Electro-Anatomical Mapping System data. The TTP06 parameters are adapted to reflect the altered electrical properties of the fibrotic tissue. To test inducibility, we use an

Identifiers

PMID42453633
PMCPMC13368414

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.