Evidence map›Paper›PMID 42454308›Full record

ArticleFrontiers in public health2026

Social determinants of vulnerability to nitrogen oxide- and sulfur dioxide-related bone damage among postmenopausal women in the United States.

Diddier Prada, Andrea Ramírez, Aravind Lathika Rajendrakumar, Andrew Maroko, James D Stewart, Duanping Liao, David Cantu-de-León, Claudia García-Cuellar, Jonathan González-Ruíz, Eric A Whitsel and 7 more

Abstract read
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Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Diddier PradaInstitute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Andrea RamírezSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, Ciudad de Mexico, Mexico.
Aravind Lathika RajendrakumarInstitute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Andrew MarokoInstitute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
James D StewartDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States.
Duanping LiaoDepartment of Public Health Science, Pennsylvania State University College of Medicine, Hershey, PA, United States.
David Cantu-de-LeónSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, Ciudad de Mexico, Mexico.
Claudia García-CuellarSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, Ciudad de Mexico, Mexico.
Jonathan González-RuízSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, Ciudad de Mexico, Mexico.
Eric A WhitselDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States.
Andrea A BaccarelliHarvard T. H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Carolyn J CrandallDivision of General Internal Medicine and Health Service Research, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States.
Haritz IrizarDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Mayte Suárez-FariñasDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Douglas KielDepartment of Medicine, Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Beth Israel Medical Center and Harvard Medical School, Boston, MA, United States.
Shivani SahniDepartment of Medicine, Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Beth Israel Medical Center and Harvard Medical School, Boston, MA, United States.
Carol R HorowitzInstitute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Studying social determinants of health (SDOH) in air pollutant-related bone loss among aging women may help identify bone health disparities, design preventive strategies, and inform policy. Prolonged exposure to air pollution is associated with decreased bone mineral density (BMD) and increased fracture risk in later life. However, the extent to which socioeconomic status (SES) contributes to pollution-related bone damage remains unclear. Methods: We estimated the extent to which social determinants of health (SDOH) modify the associations of nitrogen oxides (NOx) and sulfur dioxide (SO Results: A 10% increase in NO Conclusion: Neighborhood-level analyses revealed suggestive associations between bone mineral loss and a broader range of air pollutants. Reducing social inequities may improve the bone health of older women living in areas with high air pollution. Additional studies are needed to generalize the findings to younger women and men, as only older women were analyzed.

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureNitrogen OxidesPostmenopauseSocial Determinants of HealthSulfur DioxideAgedBone DensityFemaleHumansMiddle AgedNitrogen DioxideSocioeconomic Disparities in HealthUnited StatesAir PollutantsNitrogen DioxideNitrogen OxidesSulfur Dioxidebone mineraI densitynitrogen oxide (NO) xpostmenopausal womensocial determinants of healthsulfur dioxide

Identifiers

PMID42454308
PMCPMC13364851

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.