Evidence map›Paper›PMID 42454395›Full record

ReviewDiabetes, obesity & metabolism2026

How Common Is Hypercortisolism in Patients With Hypertension? Risk Factors, Epidemiology, and Making a Diagnosis.

Omar Al Dhaybi, Deepak L Bhatt

Abstract readReview
In one paragraph

Review in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omar Al DhaybiAHA Comprehensive Hypertension Center, Mount Sinai Fuster Heart Hospital, New York, New York, USA.ORCID 0000-0003-3748-2317
Deepak L BhattAHA Comprehensive Hypertension Center, Mount Sinai Fuster Heart Hospital, New York, New York, USA.ORCID 0000-0002-1278-6245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target-organ damage. Recent large-scale studies demonstrate a much higher prevalence of EHC among patients with resistant hypertension and difficult-to-control diabetes, often in the absence of classic Cushingoid features. This review synthesises recent large-scale epidemiological data pertaining to EHC in hypertension, and discusses the various diagnostic modalities, highlighting the need for systematic screening, which may improve outcomes in resistant hypertension.

Indexed as

Cushing SyndromeHypertensionHumansHydrocortisonePrevalenceRisk FactorsHydrocortisoneadrenal adenomaendogenous hypercortisolismhypertensionmild autonomous cortisol secretionresistant hypertension

Identifiers

PMID42454395
PMCPMC13522871

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.