Evidence map›Paper›PMID 42454791›Full record

ArticleEinstein (Sao Paulo, Brazil)2026

Intra- and inter-observer reliability of spinal inflection point localization: a cross-sectional radiographic study.

Guilherme Pianowski Pajanoti, Altacílio Aparecido Nunes, José Otávio Donadeli Tomé, Leonardo Gomes Baldoino, Lucas Dias Soares Silva, Luciano Miller Dos Reis Rodrigues, Matheus Pippa Defino

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Article in Einstein (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Guilherme Pianowski PajanotiHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7266-3415
Altacílio Aparecido NunesDepartment of Medicine, Universidade Federal de São João del Rei, Divinópolis, MG, Brazil.ORCID http://orcid.org/0000-0001-9934-920X
José Otávio Donadeli ToméDepartment of Orthopedics and Anesthesiology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0009-0006-9287-0370
Leonardo Gomes BaldoinoDepartment of Orthopedics and Anesthesiology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0009-0002-2887-0246
Lucas Dias Soares SilvaDepartment of Orthopedics and Anesthesiology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0009-0007-9174-3625
Luciano Miller Dos Reis RodriguesHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6891-5395
Matheus Pippa DefinoDepartment of Orthopedics and Anesthesiology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0001-5457-8527

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the intra- and inter-observer reliability of spinal inflection point localization on lateral radiographs of asymptomatic adults using a standardized measurement protocol, given its important role in sagittal alignment analysis and its potential influence on biomechanical interpretation and surgical planning.

methodsThis cross-sectional study included 10 adults (five males and five females; age range 32-50 years) without spinal deformities or prior spinal surgery. Lateral and anteroposterior panoramic radiographs were obtained according to the institutional protocol. Three independent orthopedic residents with less than two years of experience assessed the cervicothoracic and thoracolumbar spinal inflection points using Surgimap® software in three separate rounds, conducted at three-week intervals. The spinal inflection point was defined as the vertebral level at which curvature direction changes, according to the method described by Berthonnaud et al. Inter-observer agreement was evaluated using Cohen's kappa index with 95% confidence intervals, and intra-observer reproducibility was assessed using the intraclass correlation coefficient (ICC).

resultsThe most frequent cervicothoracic spinal inflection point was C7-T1, whereas the most common thoracolumbar spinal inflection point was T12-L1. Inter-observer agreement for the cervicothoracic spinal inflection point ranged from kappa 0.19 (95% confidence interval: -0.15 to 0.55) to 0.41 (0.05-0.75), and intra-observer ICC ranged from 0.29 (0.07-0.54) to 0.56 (0.33-0.74). For the thoracolumbar spinal inflection point, inter-observer kappa ranged from -0.03 (-0.20 to 0.14) to 0.22 (0.01-0.44), whereas ICC ranged from 0.29 (0.08-0.53) to 0.56 (0.35-0.72). Wide confidence intervals suggested low precision, likely related to the small sample size and evaluator experience.

conclusionIn this sample, localization of the spinal inflection point by non-specialist evaluators showed low intra- and inter-observer agreement, indicating limited reliability and highlighting the need for standardized protocols or additional training.

Indexed as

Cervical VertebraeLumbar VertebraeSpineThoracic VertebraeAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedObserver VariationRadiographyReference ValuesReproducibility of Results

Identifiers

PMID42454791
PMCPMC13399416

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.