Evidence map›Paper›PMID 42455157›Full record

ArticleSurgery today2026

Sex-related differences in postoperative complications after pelvic exenteration and their relationship with surgical invasiveness in a multicenter study.

Kei Kimura, Masataka Igeta, Yusuke Yatabe, Yuko Fukumoto, Kazuma Ito, Ayako Imada, Jihyung Song, Ryuichi Kuwahara, Yuki Horio, Motoi Uchino and 2 more

Abstract read
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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kei KimuraDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan. k-kimura@hyo-med.ac.jp.
Masataka IgetaDepartment of Biostatistics, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Yusuke YatabeDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Yuko FukumotoDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan.
Kazuma ItoDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan.
Ayako ImadaDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan.
Jihyung SongDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan.
Ryuichi KuwaharaDivision of Inflammatory Bowel Disease Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Japan.
Yuki HorioDivision of Inflammatory Bowel Disease Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Japan.
Motoi UchinoDivision of Inflammatory Bowel Disease Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Japan.
Yusuke KinugasaDivision of Inflammatory Bowel Disease Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Japan.
Masataka IkedaDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the sex-related differences in postoperative complications following pelvic exenteration.

methodsThis retrospective subanalysis used a multicenter registry of patients who underwent pelvic exenteration for locally advanced or recurrent rectal cancer. We included 218 patients (177 men and 41 women) in this study. The sex-related differences in postoperative complications were evaluated, and sex-by-factor interactions were assessed using logistic regression models, including sex, each perioperative factor, and the corresponding interaction term.

resultsA significant sex-by-surgical approach interaction was observed for Clavien-Dindo Grade II or higher complications (p

conclusionSex-related differences in postoperative complications after pelvic exenteration were not uniform but emerged with increased surgical invasiveness. Therefore, sex may affect the postoperative risk under conditions of increased surgical stress.

Indexed as

Pelvic exenterationRectal cancerSex differenceTME

Identifiers

PMID42455157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.