Evidence map›Paper›PMID 42455469›Full record

ArticleMedical oncology (Northwood, London, England)2026

AC3

Daiane Manica, Gilnei Bruno da Silva, Bruna Cristina Ozelame, Vitória Capelli de Mello, Vitor Asmann da Rosa, Caroline Ortmann, Isabella Del Bosco Brunetti de Camargo, Anju Majeed, Shaheen Majeed, Aniela Pinto Kempka and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daiane ManicaPostgraduate Program in Biochemistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Gilnei Bruno da SilvaMulticentric Postgraduate Program in Biochemistry and Molecular Biology, State University of Santa Catarina, Lages, SC, Brazil.
Bruna Cristina OzelamePostgraduate Program in Health Sciences, Community University of the Chapecó Region (Unochapecó), Chapecó, SC, Brazil.
Vitória Capelli de MelloPostgraduate Program in Biomedical Sciences, Federal University of Fronteira Sul, Chapecó, SC, Brazil.
Vitor Asmann da RosaPostgraduate Program in Biomedical Sciences, Federal University of Fronteira Sul, Chapecó, SC, Brazil.
Caroline OrtmannSabinsa Brasil, Florianópolis, Santa Catarina, Brazil.
Isabella Del Bosco Brunetti de CamargoSabinsa Brasil, Florianópolis, Santa Catarina, Brazil.
Anju MajeedSami-Sabinsa Group, Bangalore, Karnataka, India.
Shaheen MajeedSabinsa Corporation, Payson, UT, USA.
Aniela Pinto KempkaMulticentric Postgraduate Program in Biochemistry and Molecular Biology, State University of Santa Catarina, Lages, SC, Brazil.
Ariane ZamonerPostgraduate Program in Biochemistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Margarete Dulce BagatiniPostgraduate Program in Biochemistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil. margarete.bagatini@uffs.edu.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma (CM) poses a critical public health concern due to its high recurrence rates and resistance to standard treatments. This study investigated the antineoplastic potential of Curcuma Longa L. extract enriched with Bisdemethoxycurcumin (AC3

Indexed as

CurcuminMelanomaPlant ExtractsSkin NeoplasmsAdenosineApoptosisCell Line, TumorCell MovementCell ProliferationCell SurvivalCurcumaCutaneous Malignant MelanomaGene Expression Regulation, NeoplasticHumansInflammation MediatorsReactive Oxygen SpeciesAdenosineCurcuminInflammation MediatorsPlant ExtractsReactive Oxygen SpeciesTumor Necrosis Factor-alphaAntitumor therapyApoptosisCurcuminoidsCutaneous melanomaPurinergic signalingTNF/TNFR1 axis

Identifiers

PMID42455469
PMCPMC13372914

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.