Evidence map›Paper›PMID 42457875›Full record

ArticleLeukemia2026

Phase I, open-label, multi-center dose-finding and expansion study to investigate the safety, tolerability, and preliminary efficacy of CR-001 (5-FU-miR-15a) in patients with acute myeloid leukemia.

Irini Ktoridou-Valen, Andrea Lenartova, Sturla Magnus Grøndal, Cara E Wogsland, Adam S Dowrick, Mark Wood, Knut T Smerud, Nils Meland, Thomas Dahl, Andrew Fesler and 2 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Irini Ktoridou-ValenK.G. Jebsen Centre for Myeloid Blood Cancer CMYC, Department of Clinical Science, University of Bergen, Bergen, Norway.ORCID http://orcid.org/0009-0008-1801-7085
Andrea LenartovaK.G. Jebsen Centre for Myeloid Blood Cancer CMYC, Department of Clinical Science, University of Bergen, Bergen, Norway.
Sturla Magnus GrøndalK.G. Jebsen Centre for Myeloid Blood Cancer CMYC, Department of Clinical Science, University of Bergen, Bergen, Norway.ORCID http://orcid.org/0000-0002-7190-7377
Cara E WogslandKinN Therapeutics AS, Bergen, Norway.
Adam S DowrickSmerud Medical Research International AS, Oslo, Norway.
Mark WoodCuramir Therapeutics Inc., Lexington, MA, USA.
Knut T SmerudSmerud Medical Research International AS, Oslo, Norway.ORCID http://orcid.org/0000-0001-6647-686X
Nils MelandSmerud Medical Research International AS, Oslo, Norway.
Thomas DahlCuramir Therapeutics Inc., Lexington, MA, USA.
Andrew FeslerCuramir Therapeutics Inc., Lexington, MA, USA.
Jingfang JuStony Brook University, Department of Pathology, Renaissance School of Medicine, Stony Brook, NY, USA. jingfang.ju@stonybrookmedicine.edu.
Bjørn T GjertsenK.G. Jebsen Centre for Myeloid Blood Cancer CMYC, Department of Clinical Science, University of Bergen, Bergen, Norway. bjorn.gjertsen@uib.no.ORCID http://orcid.org/0000-0001-9358-9704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42457875
PMCPMC13506323

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.