ArticleBMC genomics2026
Comparative analysis of the complete multi-chromosomal mitogenome of an antitussive herb Fritillaria unibracteata.
Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
backgroundA renowned antitussive herb, Fritillaria unibracteata P. K. Hsiao & K. C. Hsia, has long been used as the original source of many traditional Chinese medicines (TCM) prescriptions for its pharmacological effects. Currently, this species is at risk of extinction owing to overexploitation. Genomic data can provide a scientific basis for the effective protection of wild germplasm resources. Although the plastome of F. unibracteata has been released, its mitogenome remains unclear.
resultsThe mitogenome of F. unibracteata exhibited a sophisticated multi-chromosomal configuration containing one master circular chromosome (82,085 bp) and 21 submaster chromosomes (18,718 bp-54,256 bp). It contained 60 genes, including 44 PCGs, 13 tRNA and 3 rRNA genes. Repeat sequences, including 862 dispersed repeats, 142 simple repeats, and 23 tandem repeats, contributed more to the mitogenome size than coding genes and chloroplast-derived fragments. A total of 518 RNA editing sites were identified in 36 PCGs, with NADH dehydrogenase and cytochrome c biogenesis genes being the most prevalent. The codon usage bias is in accordance with the model for most terrestrial plants that use ATG as an initiator codon and shows an obvious A/T (U) bias in the third site of all PCGs. These results provide key insights into the F. unibracteata mitogenome.
conclusionThe assembled and annotated F. unibracteata mitogenome advanced the features and organization of multi-chromosome genomes. This provides helpful information for further research on conservation, breeding, phylogenetic, and evolutionary studies of the genus Fritillaria.
Indexed as
Identifiers
42458306What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.