ArticleFrontiers in cardiovascular medicine2026
The effect of health literacy on quality of life in patients with heart failure: the mediating role of self-care confidence.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Heart failure (HF) is a global epidemic that seriously affects the quality of life (QoL) of most patients. Self-care is an important factor affecting QoL, and health literacy (HL) plays a key role in self-care. However, the relationship between HL, self-care and QoL in patients with HF remains unclear. Objectives: To explore whether self-care confidence mediates the relationship between HL and QoL in patients with HF. Methods: A total of 320 HF patients from three hospitals in Chengdu, China were selected as the research subjects. Data were collected using the Chinese version of the HF HL scale, self-care confidence scale, and QoL scale. The influencing factors of QoL were analyzed by independent samples t-test, one-way analysis of variance, and multiple linear regression. Pearson correlation analysis was used to analyze the correlation between HL, self-care confidence and QoL. Mediating effects were analyzed and validated using the PROCESS macro (Model 4) and Bootstrap method. Results: The HL score was (24.45 ± 9.44) points, the self-care confidence score was (33.66 ± 18.63) points, and the QoL score was (48.50 ± 13.32) points. HL was positively correlated with self-care confidence ( Conclusions: HL significantly impacts QoL, and self-care confidence mediates the relationship between HL and QoL. Therefore, in the care of HF patients, healthcare professionals should focus on improving patients' HL and self-care confidence. It is recommended to implement targeted health education programs for patients in clinical practice, emphasizing disease management knowledge and cultivating self-care confidence to further reduce the risk of readmission for HF patients and optimize overall prognosis.
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