Evidence mapPaperPMID 42459285Full record

ArticleFrontiers in psychiatry2026

From symptoms to function: the PAD-S decision matrix for severe mental illness-a transdiagnostic clinical translation framework for ICD-11/ICF-aligned psychotherapy documentation.

Eik Niederlohmann

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Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

1 author.

Eik NiederlohmannDepartment of Psychosomatic Medicine and Psychotherapy, Kliniken Erlabrunn, Breitenbrunn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe mental illness (SMI) is used here as a functional and service-relevant category: mental disorders associated with substantial, persistent, or recurrent restrictions in major life activities, role participation, treatment stability, or safety. Psychotherapy in SMI requires more than symptom reduction. Clinicians must repeatedly decide whether to deepen emotional work, downshift to regulation, address avoidance, protect emerging progress, or intervene against shame-driven self-attack. These decisions are clinically central but often remain poorly documented and difficult to supervise, compare, or validate. This Hypothesis & Theory manuscript proposes an SMI-specific clinical translation of the Perceive-Assess-Dose-Safeguard (PAD-S) decision matrix and the related Conflict-Square Algorithm (CSA) as a sparse, human-final decision language for such moments. PAD-S/CSA organizes session cues into four process nodes: Progression (PRO), Anxiety/Affect tolerance (ANX), Defense/Avoidance (DEF), and Superego/Shame attack (SUP). Each node is linked to tolerance thresholds, calibrated therapist moves, safeguards, and expected functional impact. The framework connects three levels without collapsing them: the International Classification of Diseases, 11th Revision (ICD-11), together with the Clinical Descriptions and Diagnostic Requirements (CDDR), anchors diagnosis and severity context; the International Classification of Functioning, Disability and Health (ICF) and the Mini-ICF-APP rating for activity and participation restrictions in mental disorders anchor activity and participation; PAD-S/CSA documents session-level process decisions. The manuscript clarifies novelty relative to related PAD-S/CSA publications, defines SMI operationally, provides plain-language node definitions, gives an SMI-specific adaptation table, illustrates a worked micro-sequence and two brief vignettes, and proposes a staged validation agenda. Digital extensions are framed as optional annotation, summarization, and research support; clinical responsibility remains human-final.

Indexed as

benchmarkingclinical decision supportcomputational psychotherapydocumentationfunctional recoveryhuman-final digital mental healthICD-11ICF

Identifiers

PMID42459285
PMCPMC13370903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.