ArticleFrontiers in oncology2026
Endoscopic submucosal dissection with deliberate muscularis propria exposure for curative resection of a large type 1 gastric neuroendocrine tumor: a case report.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The management of large (>2 cm) type 1 gastric neuroendocrine tumors (gNETs), typically associated with autoimmune gastritis, remains controversial, balancing curative intent against procedural invasiveness. This report aims to demonstrate that, with precise preoperative staging and advanced endoscopic techniques, curative organ-preserving resection is a viable option for selected cases. Case presentation: A 48-year-old female presented with markedly elevated serum gastrin (3100 pg/mL) and gastroscopy revealed two dominant lesions: a 2.5 cm lesion at the esophagogastric junction and a 1.8 cm lesion on the gastric body, the background gastric mucosa showed atrophy with scattered nodules. Comprehensive staging with endoscopic ultrasound and 68Ga-DOTATATE PET/CT, incorporating histopathology from biopsy confirming a type I gNET, G2 grade, established a localized, non-metastatic disease. After multidisciplinary discussion, the patient opted for endoscopic resection. The junctional tumor was completely removed en bloc using a tailored technique of endoscopic submucosal dissection with deliberate muscularis propria exposure (ESD-MPE), while the gastric body lesion was resected via conventional ESD. Final pathology confirmed both as pT1b, G2 NETs with all margins negative. Conclusion: For carefully selected, larger type I gNETs without metastasis, ESD-MPE represents an effective minimally invasive treatment option. This technique reflects the trend toward deeper and more precise endoscopic therapy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.