ArticleFrontiers in public health2026
Diabetes-related exposure and screening-derived abnormality burden among older rural women in Northeast China: a secondary analysis with contextual labour-type physical activity assessment.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Routine primary-care health examinations can identify clustered metabolic, renal-urinary, medication-related, and functional screening abnormalities in older adults, but their value for screening-derived abnormality-burden assessment in rural ageing populations remains underexplored. Methods: This community-based cross-sectional secondary analysis used 2025 annual health-examination data from Wangkui County, Heilongjiang Province, Northeast China. The analytic sample included 1,163 women aged ≥65 years. High screening-derived abnormality burden was constructed from routinely available screening indicators and was not intended to diagnose constipation, bowel dysfunction, frailty, or any clinical disease endpoint. Diabetes-related exposure was defined as self-reported diabetes, fasting plasma glucose ≥7.0 mmol/L, or glucose-lowering medication use. Labour-type physical activity was assessed as a secondary contextual routine-record variable using a cohort-specific index derived from weekly frequency and duration. Associations were estimated using modified Poisson regression with robust HC3 standard errors. Results: High screening-derived abnormality burden was present in 27.52% of participants, and diabetes-related exposure was present in 22.53%. Diabetes-related exposure was associated with higher abnormality burden in the primary adjusted model and remained similar after BMI adjustment (PR 1.614, 95% CI 1.329-1.961). In the key non-metabolic sensitivity analysis excluding triglycerides, HDL-C, and BMI abnormality, diabetes-related exposure remained positively associated with high non-metabolic abnormality burden (PR 1.463, 95% CI 1.077-1.988). LowActive and HighActive were not independently associated with high abnormality burden and were interpreted as contextual findings rather than as primary physical-activity evidence. Conclusion: Among older rural women, diabetes-related exposure was associated with higher screening-derived abnormality burden. Labour-type physical activity did not independently distinguish abnormality-burden status under the available crude routine-record measurement framework. This internally derived outcome should be interpreted as exploratory clustering of routine screening abnormalities for primary-care triage, not as a validated geriatric phenotype or clinical diagnostic endpoint. From an aging-and-public-health perspective, these findings suggest that routine older-adult health examinations in underserved rural communities may provide a scalable opportunity for population-level risk recognition, follow-up prioritisation, health guidance, and referral review among older women living with diabetes-related screening burden, while avoiding diagnostic over interpretation.
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