Evidence mapPaperPMID 42459839Full record

ReviewFrontiers in cell and developmental biology2026

Epitranscriptomic control of epithelial-mesenchymal transition in cancer: mechanisms, plasticity, and therapeutic opportunities.

Juan Luo, Xiulin Jiang, Chongxin Li

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan LuoDepartment of Oncology, Qujing Hospital of Traditional Chinese Medicine, Qujing, China.
Xiulin JiangCollege of Life Science, University of Chinese Academy of Sciences, Beijing, China.
Chongxin LiDepartment of Radiotherapy, Qujing Central Hospital of Yunnan Province / Kunming Medical University Affiliated Qujing Hospital, Qujing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) is a flexible cell-state program that supports tumor invasion, metastasis, immune escape, and therapy resistance. It is not a simple switch from an epithelial to a mesenchymal phenotype. Instead, cancer cells often move through intermediate or partial EMT states, which allow them to retain cell-cell adhesion while gaining motility and stress tolerance. Recent studies show that RNA modifications, including N6-methyladenosine (m

Indexed as

cancer invasioncell migrationEMTepitranscriptomicsHIF-1αhypoxiaimmune evasionRNA modification

Identifiers

PMID42459839
PMCPMC13369243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.