High-precision endoscopic optical coherence elastography with a miniaturized catheter for in vivo assessment of endometrial injury.

Qingrong Xia, Haoxing Xu, Riqiang Lin, Xiaojing Gong

Abstract read

In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Qingrong XiaAffiliated Nanhua Hospital, University of South China, Hengyang 421001, China.

Haoxing XuResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

Riqiang LinResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

Xiaojing GongResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-8221-3522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-sensitivity detection of subtle endometrial elasticity changes may provide complementary biomechanical information to enhance the assessment of benign uterine diseases within the confined uterine cavity. We report a high-precision endoscopic optical coherence elastography (E-OCE) system that integrates excitation and detection into a 0.75 mm-outer-diameter probe, enabling minimally invasive transcervical intrauterine imaging in small animals without laparotomy. A λ-triggered depth-correlated phase-correction method reduces the minimum detectable elasticity change from 6.3% to 1.3%. Agar phantoms show close agreement with mechanical testing, and in vivo rat imaging effectively resolves graded endometrial injury. These pilot results suggest that a miniature intrauterine E-OCE system can resolve graded endometrial injury in the rat model, providing a basis for further preclinical investigation of endometrial biomechanical imaging.

Identifiers

PMID42460355

DOI10.1364/BOE.604355

PMCPMC13372384

What Socratic holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.