Evidence map›Paper›PMID 42460359›Full record

ArticleBiomedical optics express2026

Seedling fibroid characterization using optical coherence tomography.

Arielle S Joasil, Daniella M Fodera, Zhuoya Shi, Sunny Hu, Aidan M Therien, Haiqiu Yang, Xiaowei Chen, Kristin M Myers, Christine P Hendon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arielle S JoasilColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.ORCID https://orcid.org/0009-0003-8663-4679
Daniella M FoderaColumbia University, Department of Biomedical Engineering, 500 W 120th St, New York, NY, USA.
Zhuoya ShiColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.
Sunny HuColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.
Aidan M TherienColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.
Haiqiu YangColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.
Xiaowei ChenColumbia University Irving Medical Center, Department of Pathology and Cell Biology, 622 W 168th St, New York, NY, USA.
Kristin M MyersColumbia University, Department of Mechanical Engineering, 500 W 120th St, New York, NY, USA.
Christine P HendonColumbia University, Department of Electrical Engineering, 500 W 120th St, New York, NY, USA.

Funding

Biomechanics and mechanobiology of human uterine fibroidsF31HD114449 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI FODERA, DANIELLA M · 2024 to 2025
$99k
NICHD NIH HHS F31 HD114449
6 · The paper itself

Abstract

Uterine leiomyomas, or fibroids, are the most common benign tumors in women. Despite this, the patient and healthcare burdens are immense. Symptoms include heavy and irregular bleeding, anemia, and impacts on fertility. Treatment options are limited, and fibroids are typically treated with hysterectomy. Current imaging modalities used for diagnosis and surgical planning cannot resolve smaller, or seedling, fibroids. If fibroids remain after surgery, they can continue to grow and require additional interventions. In this work, we characterize human seedling fibroids using optical coherence tomography (OCT). Statistical testing reveals significant differences between fibroid and normal specimens in OCT-based texture, statistical, and frequency-based features, as well as in collagen fiber architecture quantification. With its micron-resolution and near-real-time imaging speed, OCT has the potential to elucidate the microstructural characteristics of seedling fibroids, aiding in diagnosis and surgical planning.

Identifiers

PMID42460359
PMCPMC13372371

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.