ArticleActa odontologica Scandinavica2026
Association of periodontal condition with insulin sensitivity - results of the Oulu1935 cohort study.
Article in Acta odontologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate whether baseline periodontal condition predicts reduced insulin sensitivity (RIS) over a follow-up period of about 15 years among participants with baseline euglycemia. MATERIAL AND
methodsA subpopulation (n = 224) of the Oulu1935 cohort was studied. Periodontal condition was defined by the presence and number of sites with periodontal pockets (probing pocket depth ≥ 4 mm) or by the participant being edentulous. Insulin sensitivity was measured using the Quantitative Insulin Sensitivity Check Index, with the lowest tertile indicating RIS. Rate ratios (RRs) with 95% confidence intervals (CI) were estimated using Poisson regression models with a robust error variance.
resultsRIS was observed in 21.3% of the dentate participants without periodontal pockets, 32.8% of those with 1-6 sites with pockets, 33.3% of those with ≥ 7 sites with pockets, and 40.8% of the edentulous participants. Furthermore, adjusted RRs with 95% CIs (in parentheses) for the association of periodontal condition with RIS (reference: dentate participants without periodontal pockets) were 1.4 (0.8-2.6), 1.1 (0.6-2.1), and 1.4 (0.8-2.7), respectively.
conclusionsPoor periodontal condition and edentulousness predicted RIS. A healthy periodontium appears to support normal insulin function, but further studies are needed.
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