Evidence map›Paper›PMID 42461027›Full record

ArticleMicrobiology spectrum2026

A human-derived Pseudorabies virus isolate induces Cav2.2-sensitive Ca

Chuyue Zhou, Hang Li, Lang Tian, Hao Zhang, Ruicheng Yang, Huanchun Chen, Xiangru Wang

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuyue ZhouNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.ORCID 0009-0000-2820-6770
Hang LiNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Lang TianNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Hao ZhangNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Ruicheng YangNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Huanchun ChenNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Xiangru WangNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.ORCID 0000-0003-0191-1378

Funding

Earmarked Fund for China Agriculture Research System CARS-35Fundamental Research Funds for the Central Universities 2662025DKPY009, 2662025PY001National Key Research and Development Program of China 2021YFD1800800National Natural Science Foundation of China 32473031, 32122086Scientific Research Innovation Capability Support Project for Young Faculty ZYGXQNJSKYCXNLZCXM-A4
6 · The paper itself

Abstract

Pseudorabies virus (PRV), the etiological agent of Aujeszky's disease, remains a major threat to the swine industry. Several human PRV infections have recently been reported, including cases with severe ocular involvement, but how human-derived PRV isolates injure retinal cells remains poorly understood. Here, we used the human-derived PRV isolate hSD-1/2019 and ARPE-19 cells to define an injury-associated Ca

Indexed as

CalciumCaveolin 2Epithelial CellsHerpesvirus 1, SuidRetinaAnimalsCell LineHumansSwineCalciumCaveolin 2ARPE-19Ca2+ influxCav2.2glycoprotein KPseudorabies virusretinal epithelial injury

Identifiers

PMID42461027
PMCPMC13436308

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.