Evidence map›Paper›PMID 42465474›Full record

ArticlebioRxiv : the preprint server for biology2026

The endothelial scavenger receptor

Gwendolyn M Beacham, Zewde S Ingram, Reema A Elrefaie, Khaliun Enkhbayar, Zachary R Zener, Leila Affini, Zainab N Wasim, Maura C Dodge, Sandeep Sreerama, Maria A Serrano and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gwendolyn M BeachamDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0001-7158-6887
Zewde S IngramDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0003-3615-0273
Reema A ElrefaieDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0009-0009-0294-4164
Khaliun EnkhbayarDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0009-0002-4802-1348
Zachary R ZenerDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0009-0002-6808-9315
Leila AffiniDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0009-0005-7497-9690
Zainab N WasimDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0009-0001-3028-6076
Maura C DodgeDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0002-2348-9465
Sandeep SreeramaCenter for Regenerative Medicine, Department of Medicine, Section of Vascular Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.ORCID 0000-0002-2527-4636
Maria A SerranoCenter for Regenerative Medicine, Department of Medicine, Section of Vascular Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.ORCID 0000-0002-4318-3746
Elliott J HagedornDepartment of Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0002-3824-3249

Funding

NRSA Training CoreTL1TR001410 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOTTON, DARRELL N. · 2015 to 2024
$4.3M
Niche-specific endothelial mechanisms regulating the extravasation of hematopoietic stem cellsR01HL178832 · NHLBI · BOSTON MEDICAL CENTER · PI Elliott Jennings Hagedorn · 2025 to 2026
$1.4M
Deconstructing the Hematopoietic Stem Cell NicheK01DK111790 · NIDDK · BOSTON MEDICAL CENTER · PI HAGEDORN, ELLIOTT JENNINGS · 2017 to 2021
$792k
Full Spectrum Cell Sorter with Imaging Enhancement for Boston University Flow Cytometry Core FacilityS10OD038346 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BELKINA, ANNA · 2025 to 2025
$656k
Mechanisms of a conserved niche endothelial program directing hematopoietic stem cell migrationF31HL184822 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Zewde Ingram · 2026 to 2026
$50k
NCATS NIH HHS TL1 TR001410NHLBI NIH HHS F31 HL184822NHLBI NIH HHS R01 HL178832NIDDK NIH HHS K01 DK111790NIH HHS S10 OD038346
6 · The paper itself

Abstract

Hematopoietic stem and progenitor cell (HSPC) niches support lifelong production of blood and immune cells. Recently, we identified a gene signature unique to HSPC niche endothelial cells that is highly conserved across species and developmental time and includes the scavenger receptors

Indexed as

blood stem cell nicheerythroid developmentHematopoietic developmentscavenger receptorszebrafish

Identifiers

PMID42465474
PMCPMC13370947

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.