SynthesisFrontiers in neurology
Early emotional interventions for post-stroke functional prognosis: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background: Post-stroke emotional disorders (PSEDs) impair functional recovery, but the optimal type and timing of early interventions remain unclear. This study aimed to determine the efficacy of early emotional interventions on functional outcomes in stroke patients and to examine whether benefits differ by intervention type and timing of initiation. Methods: In this systematic review and meta-analysis, we searched seven databases for randomized controlled trials (RCTs) up to November 2025. We included adults with acute/subacute stroke (≤ 3 months) assigned to an emotional intervention (pharmacological, psychological, neuromodulation, or combined) versus control. The primary outcome was the change in Barthel Index (BI) at follow-up. Results: Thirty-eight RCTs ( Conclusion: Early emotional interventions significantly improve functional recovery after stroke, with the greatest benefit observed for cognitive behavioral therapy and combined interventions initiated within 2 weeks of stroke onset. These findings support the integration of targeted emotional interventions into early standard care.
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