Evidence mapPaperPMID 42465635Full record

ArticleFrontiers in public health2026

From innovation network to public health benefit: evolutionary characteristics and optimization of the biomedical industry innovation network in the Beijing-Tianjin-Hebei region.

Xinfei Xie, Mingmei Xiang, Qingli Tan

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinfei XieSchool of Pharmaceutical Business, Guangdong Pharmaceutical University, Guangzhou, China.
Mingmei XiangSchool of Pharmaceutical Business, Guangdong Pharmaceutical University, Guangzhou, China.
Qingli TanSchool of Pharmaceutical Business, Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As a core component of strategic emerging industries, the biomedical industry serves as a key indicator of regional scientific and technological innovation capacity and industrial competitiveness. The Beijing-Tianjin-Hebei (BTH) region possesses inherent advantages for development, including abundant research resources, a solid industrial foundation, and vast market potential. However, it also faces structural challenges such as insufficient collaboration within innovation networks and resource misallocation. Methods: Based on multi-source data, including patent data and enterprise panel data from 2013 to 2023, this paper systematically analyzes the evolutionary characteristics of the BTH biomedical industry innovation network and identifies obstacles to its high-quality development. Methods such as social network analysis (SNA), the Temporal Exponential Random Graph Model (TERGM), and an obstacle degree model are employed. Results: The study finds that the regional innovation network has evolved from a "dual-core monopoly" (2013-2018) to a "Beijing-Tianjin-Xiong'an triangle structure" emerging by 2023 forming a multi-level collaborative pattern. However, the main obstacles lie in the low efficiency of R&D personnel, insufficient conversion of patent revenue, and inadequate cross-regional policy coordination, with disconnections existing in the "R&D-conversion-industrialization" chain. Discussion: To address these issues, this paper proposes strengthening the precise division of labor system: "Beijing for R&D, Tianjin for conversion, and Hebei for manufacturing" to improve full-chain innovation services to bridge conversion gaps, optimizing resource allocation to resolve mismatches, and implementing differentiated policies. From a public health perspective, these measures are designed to shorten the R&D-to-registration cycle, lower the cost of essential medicines, and reduce interregional health disparities. By accelerating the translation of biomedical innovations into accessible diagnostics, vaccines, and therapeutics, the optimized innovation network can directly enhance regional health security and epidemic response capacity. This aims to promote high-quality and coordinated regional industrial development, ultimately con tributing to improved public health outcomes by accelerating the translation of R&D into accessible diagnostics, vaccines, and therapeutics, and strengthening regional health security.

Indexed as

Biomedical ResearchInventionsPublic HealthBeijingChinaHumansSocial Network AnalysisBeijing-Tianjin-Hebei regionbiomedical industryinnovation network evolutionobstacle factorspublic health translationregional health equitysocial network analysis (SNA)Temporal Exponential Random Graph Model (TERGM)

Identifiers

PMID42465635
PMCPMC13372913

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.