Evidence map›Paper›PMID 42465850›Full record

ReviewFrontiers in reproductive health2026

Non-invasive biomarkers in assisted reproductive technologies, current evidence, clinical utility and future perspectives.

Athanasios Zikopoulos, Athanasia Sesse, Periklis Katopodis, Ariadni Theodora Katopodi, Vasilis Sebastian Paraschos, Maria Filiponi, Ioanna Bouba, Charilaos Kostoulas, Athanasios Zachariou, Ioannis Georgiou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Athanasios ZikopoulosLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Athanasia SesseLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Periklis KatopodisLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Ariadni Theodora KatopodiLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Vasilis Sebastian ParaschosDepartment of Obstetrics and Gynecology, Corewell Health Hospital, Dearborn, MI, United States.
Maria FiliponiLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Ioanna BoubaLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Charilaos KostoulasLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Athanasios ZachariouDepartment of Urology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Ioannis GeorgiouLaboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although assisted reproductive technologies have significantly advanced the treatment of infertility, overall success rates remain limited by the lack of accurate and safe tools for assessing reproductive potential. Conventional embryo selection and endometrial evaluation rely largely on morphological and non-functional criteria, which provide only indirect insight into the underlying biological competence of the embryo oocyte and uterine environment. In this context the development of non-invasive biomarkers has emerged as a critical objective in modern reproductive medicine. This review discusses current evidence on non-invasive biomarkers in

Indexed as

artificial intelligence in IVFassisted reproductive technologiesembryo selectionendometrial receptivityfollicular fluidin vitro fertilizationnon-invasive biomarkersomic technologies

Identifiers

PMID42465850
PMCPMC13372965

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.