Evidence mapPaperPMID 42466006Full record

ArticleNeurology research international2026

Effect of Foot Reflexology on Restless Legs Syndrome and Sleep Quality in Female Patients With Multiple Sclerosis: A Randomized, Double-Blind Clinical Trial.

Fatemeh Harandi, Batool Tirgari, Yunes Jahani, Haleh Tajadini

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In one paragraph

Article in Neurology research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatemeh HarandiPhysiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran, kmu.ac.ir.ORCID https://orcid.org/0000-0003-2686-6569
Batool TirgariNursing Research Center, Kerman University of Medical Sciences, Kerman, Iran, kmu.ac.ir.ORCID https://orcid.org/0000-0002-0572-5233
Yunes JahaniModelling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran, kmu.ac.ir.ORCID https://orcid.org/0000-0002-6808-7101
Haleh TajadiniNeuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran, kmu.ac.ir.ORCID https://orcid.org/0000-0002-9125-684X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This clinical trial aimed to assess the effectiveness of foot reflexology on restless legs syndrome and sleep quality in patients with multiple sclerosis. Materials and Methods: Sixty-four female patients with multiple sclerosis were randomly assigned to the intervention or sham group. Foot reflexology was taught to the intervention group; it was performed for 4 weeks, three times a week for 26 min each session, by a trained researcher in the morning shift and on three other days in the afternoon at home by the patients themselves. Moreover, the sham group received nonspecific foot massage without applying pressure to the standard reflexology points under similar conditions and durations as those of the intervention group. Data were collected before, immediately after, and 1 month after intervention. Results: The results revealed a significant improvement in sleep quality ( Conclusions: Nurses should be trained in foot reflexology as a noninvasive approach that can be easily implemented.

Indexed as

multiple sclerosisreflexologyrestless leg syndromesleep quality

Identifiers

PMID42466006
PMCPMC13373438

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.