Evidence map›Paper›PMID 42466137›Full record

ArticleFrontiers in nutrition2026

Association between serum minerals and malnutrition assessed by GLIM among hospitalized adults: a multicenter cross-sectional study.

Hongmei Xue, Xinyu He, Huanyu Hu, Ying Wang, Ying Xie, Dandan Wang, Zhicui Yao, Chunhua Song, Wei Chen, Zengning Li

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Hongmei XueDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Xinyu HeSchool of Public Health, Hebei Medical University, Shijiazhuang, China.
Huanyu HuDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Ying WangDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Ying XieDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Dandan WangDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Zhicui YaoSchool of Nursing, Hebei University of Chinese Medicine, Shijiazhuang, China.
Chunhua SongDepartment of Epidemiology and Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Wei ChenDepartment of Clinical Nutrition, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Zengning LiDepartment of Clinical Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the relationship between single- and multiple-mineral deficiencies and malnutrition, as defined by the Global Leadership Initiative on Malnutrition (GLIM) criteria among Chinese inpatients. Methods: A multicenter cross-sectional study of hospitalized patients in hospitals was conducted in China. Information on the inpatients' social demographic characteristics, physical examination, and laboratory test results was collected. Malnutrition was defined on the GLIM criteria. Multivariable logistic regression and restricted cubic spline were used to examine the relationship between individual serum minerals and their counts and malnutrition. Results: A total of 3,433 hospitalized adults were included in the study. Compared to those with normal mineral levels, patients with serum mineral deficiencies had a 1.43- to 2.31-fold higher likelihood of prevalent GLIM-based malnutrition. After stratifying by age, significant associations were observed only among middle-aged and elderly inpatients. For individuals aged 45 and older, low mineral levels were associated with a higher likelihood of malnutrition compared to normal levels; the ORs (95% CIs) ranged from 1.56 (1.01, 2.39) to 2.96 (1.71, 5.70). Furthermore, inpatients with one, two, and three or more minerals below the normal level had a respective 1.33-, 2.15-, and 2.95-fold higher likelihood of prevalent malnutrition, respectively. Conclusion: Our study found that serum mineral deficiencies-particularly potassium, sodium, chloride, and phosphorus-are significantly associated with prevalent malnutrition, with this association more pronounced among middle-aged and elderly patients. Moreover, the cumulative burden of mineral deficiencies showed a graded association with the likelihood of prevalent malnutrition, though this association requires further validation in prospective studies.

Indexed as

adultglobal leadership initiative on malnutritionhospitalizedmalnutritionmineral

Identifiers

PMID42466137
PMCPMC13374522

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.