Evidence map›Paper›PMID 42466371›Full record

ArticleHealth science reports2026

Weight Loss Plateau: Reasons, Challenges, and Solutions: A Narrative Review.

Damoon Ashtary-Larky, Shooka Mohammadi

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Damoon Ashtary-LarkyNutrition and Metabolic Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0001-7968-6110
Shooka MohammadiNutrition and Metabolic Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0001-9157-1922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Weight loss plateau (WLP) is one of the most significant obstacles for individuals with overweight and obesity during weight loss (WL). Preventing WLP is essential for maintaining long-term WL and minimizing the risk of weight regain. Despite the widespread challenge of combating obesity and barriers to WL, this area has received limited attention in research. Therefore, the present narrative review discusses the reasons, challenges, and management of WLP, which often occurs alongside diet-induced WL. Methods: A comprehensive literature search was conducted using search strategies and keywords to identify studies published until January 2025 in several databases. Data were synthesized using a narrative review approach. Given the descriptive and exploratory nature of this review, no formal methodological quality or risk of bias assessment was performed for the included studies. Results: WLP typically emerges approximately 6-8 months into WL programs, although this timeline may vary among individuals. In addition to individual differences related to WLP, even with adherence to dietary and lifestyle modifications, WLP can occur primarily due to metabolic adaptations. These adaptations occur because a reduction in dietary intake decreases all components of total energy expenditure (TEE). Furthermore, calorie restriction can increase appetite and hunger. Reductions in TEE, combined with increased appetite, contribute to the development of an energy gap. Factors such as initial WL, previous WL experiences, a tendency toward passive overconsumption of calories, behavioral changes and genetic factors can contribute to an earlier WLP. Although all components of TEE decrease during WL, the most significant reduction is often observed in non-exercise activity thermogenesis (NEAT). Conclusion: Several strategies may help address metabolic adaptation and prevent and manage WLP. These include caloric reduction, high-protein diets, gradual WL, planned overfeeding, increased physical activity, maintenance of reduced body weight, body recomposition, nonlinear dieting approaches, and appetite-regulating dietary plans.

Indexed as

calorie restrictionmetabolic adaptationnon‐exercise activity thermogenesisobesityweight lossweight loss plateau

Identifiers

PMID42466371
PMCPMC13373534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.