Evidence map›Paper›PMID 42466391›Full record

ArticleResearch square2026

Motor and Cognitive Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke.

Amanda Chirino-Pérez, Christina Merrick, Fredy Miranda-Casasola, Ludovica Labruna, Richard B Ivry

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Amanda Chirino-PérezUniversity of California, Berkeley.
Christina MerrickMagnetic Tides Inc.
Fredy Miranda-CasasolaUniversidad Nacional Autónoma de México.
Ludovica LabrunaMagnetic Tides Inc.
Richard B IvryUniversity of California, Berkeley.

Funding

Human Cerebellar Function in Multiple Task DomainsR35NS116883 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD IVRY · 2020 to 2026
$5.3M
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity.R44NS127667 · NINDS · MAGNETIC TIDES, INC. · PI LABRUNA, LUDOVICA · 2022 to 2025
$3.6M
A Novel Method of Non-Invasive Brain Stimulation to Enhance Motor Function in Chronic Stroke PatientsR44NS139730 · NINDS · MAGNETIC TIDES, INC. · PI Ludovica Labruna · 2025 to 2026
$1.8M
NINDS NIH HHS R35 NS116883NINDS NIH HHS R44 NS127667NINDS NIH HHS R44 NS139730
6 · The paper itself

Abstract

Cerebellar ataxia results in debilitating impairments in balance, gait, and cognition, with no established effective treatments. Kilohertz transcranial magnetic perturbation (kTMP) is a novel subthreshold non-invasive brain stimulation (NIBS) method that delivers strong, subthreshold electric fields to the cerebellar cortex without discomfort. We present the case of a 78-year-old patient with cerebellar ataxia following hemorrhagic stroke who underwent amplitude-modulated kTMP (AM-kTMP) targeted to vermal and paravermal cerebellar regions. Active AM-kTMP produced improvements on clinical scales of ataxia alongside enhanced gait stability and cognitive performance, with no device-related adverse reactions, representing a promising NIBS intervention for cerebellar disorders.

Indexed as

Cerebellar ataxiaCerebellar Cognitive Affective SyndromeNon-invasive brain stimulationPostural stabilityStroke

Identifiers

PMID42466391
PMCPMC13370616

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.