Evidence map›Paper›PMID 42467331›Full record

Observational studySleep & breathing = Schlaf & Atmung2026

Prevalence and management of residual respiratory events in OSA patients treated with CPAP: a prospective observational clinical experience.

S Hondeghem, T Mettay, C Espana-Dominguez, A V Bruyneel, Marie Bruyneel

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S HondeghemDepartment of Pulmonary Medicine, Brugmann University Hospital, Brussels, Belgium.
T MettayDepartment of Pulmonary Medicine, Brugmann University Hospital, Brussels, Belgium.
C Espana-DominguezDepartment of Pulmonary Medicine, Brugmann University Hospital, Brussels, Belgium.
A V BruyneelGeneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, 1206, Geneva, Switzerland.
Marie BruyneelDepartment of Pulmonary Medicine, Brugmann University Hospital, Brussels, Belgium. marie.bruyneel@stpierre-bru.be.ORCID http://orcid.org/0000-0002-7035-1266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeResidual respiratory events (RREs) are common in continuous positive airway pressure (CPAP) users. They can lead to poor CPAP adherence and early termination. The management of RREs has not been standardized yet. The purpose of this study was to test a structured management algorithm for RREs detected by CPAP devices in OSA patients.

methodsThis was a prospective observational clinical study that aimed to test a specific algorithm in patients exhibiting RREs. This study also included a case-control comparison. Cases were OSA patients (AHI ≥ 15) exhibiting RREs (AHI

resultsA total of 19/273 patients exhibited RREs. Compared to matched controls, cases had higher RREs on titration PSG and used more often naso-buccal masks (p < 0.05). Among the 19 RRE patients, predominant obstructive AHI

conclusionsOnce leaks are controlled, occurrence of RREs in compliant CPAP users is uncommon. A structured algorithm helped clarify the likely mechanism of device-detected RREs and guided individualized management during the first months of CPAP therapy. The most common cause of RRE was insufficient CPAP pressure, but cases of COMISA and of "idiopathic" central sleep apnea (CSA)/CSR also occurred that required specific management.

Indexed as

Continuous Positive Airway PressureSleep Apnea, ObstructiveAdultAgedAlgorithmsCase-Control StudiesFemaleHumansMaleMiddle AgedPatient CompliancePolysomnographyProspective StudiesCentral sleep apneaCheyne-Stokes respirationComplianceContinuous positive airway pressureObstructive sleep apnea syndromeResidual respiratory eventsTelemonitoring

Identifiers

PMID42467331
PMCPMC13379486

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.