Evidence map›Paper›PMID 42469032›Full record

ArticleeNeuro2026

Altered

Katie Brandel-Ankrapp, Rachel N Arey

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Katie Brandel-AnkrappDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.
Rachel N AreyCenter for Precision Environmental Health, Baylor College of Medicine, Houston, Texas 77030 rachel.arey@bcm.edu.ORCID https://orcid.org/0000-0001-9941-3945

Funding

Uncovering brain-wide molecular determinants of individual memory performance across lifespanDP2NS132372 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI AREY, RACHEL NICOLE · 2022 to 2025
$2.4M
NINDS NIH HHS DP2 NS132372
6 · The paper itself

Abstract

Chronic ethanol (EtOH) exposure and withdrawal are linked to worsened memory and cognitive outcomes. One target of EtOH is the glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR). Both EtOH exposure and withdrawal influences AMPAR expression, function, and broad glutamate signaling. Previous work suggests that EtOH regulation of AMPARs drives behaviors related to dependence and memory phenotypes. However, due to the complexity of the mammalian brain, it is difficult to unravel the precise mechanism by which EtOH regulates AMPARs in mammals to modify specific memory behaviors. In

Indexed as

Association LearningCaenorhabditis elegans ProteinsCentral Nervous System DepressantsEthanolReceptors, AMPASubstance Withdrawal SyndromeAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCyclic AMP Response Element-Binding ProteinMemorySignal TransductionCaenorhabditis elegans ProteinsCentral Nervous System DepressantsCyclic AMP Response Element-Binding ProteinEthanolglr-1 protein, C elegansReceptors, AMPAAMPA receptorsC. elegansCREBethanolkinaselearning and memory

Identifiers

PMID42469032
PMCPMC13423511

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.